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老年2型糖尿病患者尿路感染的临床特点及相关因素分析
  • ISSN号:1005-4529
  • 期刊名称:《中华医院感染学杂志》
  • 时间:0
  • 分类:R691.3[医药卫生—泌尿科学;医药卫生—临床医学;医药卫生—外科学]
  • 作者机构:[1]浙江省玉环县第二人民医院内分秘科,浙江玉环县317605
  • 相关基金:浙江省玉环县科技计划基金项目(2012008)
中文摘要:

目的了解老年2型糖尿病(T2DM)患者尿路感染(UTI)的临床特点,并对相关危险因素进行分析,为临床资料提供参考依据。方法回顾性分析2010年2月-2012年4月1075例老年T2DM患者临床资料,合并UTI患者为病例组(132例),非UTI患者为对照组(943例),比较两组患者临床特征、病原学特点,并对相关危险因素作logistic回归分析。结果1075例老年T2DM患者发生UTI132例,发生率为12.3%,与对照组比较,病例组年龄、糖尿病病程、血糖、糖化血红蛋白、血肌酐及尿路结石比例差异均有统计学意义(P〈0.05);无症状性uTI患者有48例,占36.3%;尿培养共检出病原菌152株,其中革兰阴性菌95株62.5%,革兰阳性菌49株32.2%,真菌8株5.3%;多因素logistic回归分析显示,糖尿病病程(OR=4.209)、血糖水平(OR=2.254)及合并泌尿系结石(OR=1.741)是T2DM患者发生uTI的独立危险因素。结论老年T2DM患者UTI发生率较高,部分患者无典型症状,革兰阴性菌是最常见的病原菌,血糖高、糖尿病病程长和泌尿系结石是T2DM患者发生UTI的独立危险因素。

英文摘要:

OBJECTIVE To explore the clinical characteristics of urinary tract infections in elderly patients with type 2 diabetes and analyze the related risk factors so as to provide guidance for clinical data. METHODS From Feb 2010 to Apr 2012, the clinical data of 1075 elderly patients with type 2 diabetes were retrospectively analyzed, then the patients complicated with urinary tract infections were assigned as the case group (132 cases), the patients without urinary tract infections were set as the control group (943 cases), the clinical and etiological char- acteristics were observed and compared between the two groups, and the logistie regression analysis was per- formed to analyze the related risk factors. RESULTS Of the 1075 elderly patients with type 2 diabetes, the urinary tract infections occurred in 132 cases with the incidence rate of 12.3%. The difference in the age, course of diabe- tes, blood glucose, glycated hemoglobin, blood creatinine, or proportion of urinary lithiasis between the ease group and the control was statistieally significant (P〈0.05). There were 48 (36. 3%) cases of asymptomatic urinary tract infections. Totally 152 strains of pathogens have been isolated from urine culture, including 95 (62.5%) strains of gram-negative bacteria, 49 (32.2%) strains of gram-positive bacteria, and 8 (5.3%) strains of fungi. The multivariate logistic regression analysis indicated that the course of diabetes (OR=4. 209), level of blood glucose(OR=2. 254), and complication of urinary lithiasis(OR= 1. 741) were the independent risk factors for the urinary tract infections in the patients with type 2 diabetes. CONCLUSION The incidenee of urinary tract infections is high in the elderly patients with type 2 diabetes, and some of the patients are with asymptomatic symptoms. The gram-negative bacteria are the most common pathogens. The high level of blood glucose, long course of diabetes, and urinary lithiasis are the independent risk factors for the urinary tract infections i

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期刊信息
  • 《中华医院感染学杂志》
  • 北大核心期刊(2011版)
  • 主管单位:中国人民解放军总医院
  • 主办单位:中华预防医学会
  • 主编:
  • 地址:北京复兴路28号
  • 邮编:100039
  • 邮箱:zhyygrxzz@21cn.com
  • 电话:010-66939464
  • 国际标准刊号:ISSN:1005-4529
  • 国内统一刊号:ISSN:11-3456/R
  • 邮发代号:82-747
  • 获奖情况:
  • 中华预防医学会期刊评比优秀奖,中华预防医学会期刊评比编辑奖,中华预防医学会期刊评比学术奖
  • 国内外数据库收录:
  • 美国化学文摘(网络版),英国农业与生物科学研究中心文摘,波兰哥白尼索引,美国剑桥科学文摘,日本日本科学技术振兴机构数据库,中国中国科技核心期刊,中国北大核心期刊(2004版),中国北大核心期刊(2008版),中国北大核心期刊(2011版),中国北大核心期刊(2014版)
  • 被引量:111886