目的:比较壳聚糖、ZTC1+1-Ⅲ、101果汁澄清剂3种天然澄清剂对醒鼻方水提取液的除杂效果,以优选出醒鼻方水提液的最佳纯化方法。方法:以丹皮酚保留率、药液澄清情况等为考察指标,对3种天然澄清剂的除杂效果进行了比较研究。结果:采用壳聚糖除杂后的药液较为澄清,且对丹皮酚保留率略高,101果汁澄清剂、ZTC1+1-Ⅲ对丹皮酚保留率无太大的差别。结论:用量10%的壳聚糖用于醒鼻方水提取液除杂效果最佳。
Objective:To optimize the precipitation process of the extract of Xingbi gels using chitosan,ZTC1+1-Ⅲ and 101 syrup clearing medium natural clearing medium.Methods:Using the remaining rates of paeonol and the defecation level as indexes,the optimum process of removing impurity was investigated.Results:The effect of purification by chitosan was significant,the remaining ratio of active ingrediect was higher than 101 syrup clearing medium and ZTC1+1-Ⅲ.Conclusion:The concentration of chitosan at 10% can be used to effectively remove the impunity of extract of Xingbi gels.