炎症反应在脑缺血后继发性脑损伤中发挥关键作用,其中,小胶质细胞激活和极化起着重要作用。文章对脑缺血后小胶质细胞在炎症方面的作用以及小胶质细胞激活和极化的分子机制进行了综述。
Inflammation plays a key role in the secondary brain injury after cerebral ischemia, in which microglia activation and polarization play important roles. This article reviews the roles of microglia in inflammation and the molecular mechanisms of microglia activation and polarization after cerebral ischemia.