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Relationship between the Expression of Thymidylate Synthase,Thymidine Phosphorylase and Dihydropyrimidine Dehydrogenase and Survival in Epithelial Ovarian Cancer
  • ISSN号:1000-8578
  • 期刊名称:《肿瘤防治研究》
  • 时间:0
  • 分类:R737.31[医药卫生—肿瘤;医药卫生—临床医学]
  • 作者机构:[1]Department of Obstetrics and Gynecology Tongji Hospital Tongji Medical College Huazhong University of Science and Technology
  • 相关基金:supported by a grant from the National Natural Sciences Foundation of China (No. 30973184)
中文摘要:

The mRNA and protein expression of thymidylate synthase (TS), thymidine phosphorylase (TP) and dihydropyrimidine dehydrogenase (DPD) and their relationship with prognosis were investigated. Real-time quantitative RT-PCR (Taqman) was used to detect the mRNA expression of TS, TP and DPD in formalin-fixed and paraffin-embedded 106 samples of epithelial ovarian cancer and 29 normal ovaries. A TATA box-binding protein (TBP) was used as an endogenous reference gene. A relationship between TS, TP, DPD expression a...

英文摘要:

The mRNA and protein expression of thymidylate synthase (TS), thymidine phosphorylase (TP) and dihydropyrimidine dehydrogenase (DPD) and their relationship with prognosis were investigated. Real-time quantitative RT-PCR (Taqman) was used to detect the mRNA expression of TS, TP and DPD in formalin-fixed and paraffin-embedded 106 samples of epithelial ovarian cancer and 29 normal ovaries. A TATA box-binding protein (TBP) was used as an endogenous reference gene. A relationship between TS, TP, DPD expression a...

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期刊信息
  • 《肿瘤防治研究》
  • 中国科技核心期刊
  • 主管单位:中华人民共和国卫生部
  • 主办单位:湖北省卫生厅 中国抗癌协会 湖北省肿瘤医院
  • 主编:魏少忠
  • 地址:武昌卓刀泉南路116号
  • 邮编:430079
  • 邮箱:zlfzyj@263.net.cn
  • 电话:027-87670126
  • 国际标准刊号:ISSN:1000-8578
  • 国内统一刊号:ISSN:42-1241/R
  • 邮发代号:38-70
  • 获奖情况:
  • 中国学术期刊综合评价数据库来源期刊,中国科学引文数据库来源期刊
  • 国内外数据库收录:
  • 美国化学文摘(网络版),英国农业与生物科学研究中心文摘,波兰哥白尼索引,美国剑桥科学文摘,日本日本科学技术振兴机构数据库,中国中国科技核心期刊,中国北大核心期刊(2004版),中国北大核心期刊(2008版),中国北大核心期刊(2011版),中国北大核心期刊(2014版)
  • 被引量:17449