阿尔茨海默病(Alzheimer’s disease,AD)病因及发病机制尚未完全阐明,有关其发病机制有β-淀粉样蛋白假说、Tau 蛋白假说、炎症学说和氧化应激学说等多种.本文就现有较公认的发病机制研究进展作一综述.
Although the pathogenesis of Alzheimer’s Disease (AD) is unclear, several hypotheses have been proposed, including theβ-amyloid cascade theory, Tau protein hypothesis, inflammation hypothesis and oxidative stress theory. This review summarized the widely-accepted new viewpoints on the pathogenesis of AD.