中文摘要：

目的调查不同地区青年男性进藏后急性高原反应（AMS）的发生情况,探讨不同地区人群高原环境适应能力的医学地理学差异。方法对从不同地区进入高原的青年男性AMS发生情况进行整群抽样调查,参照军用标准,采用AMS症状学评分法对其进行分度与评分。为区分不同地理环境差异,对人员生活所在地自然地理因素进行系统聚类分析,并用非参数检验进行验证。采用单因素方差分析研究不同地区青年男性AMS症状评分的差异。结果根据聚类分析结果将研究对象生活所在地分为5个地区,各组地理指标之间差异具有统计学意义（P〈0.01）。研究显示不同地区人群AMS的发生率存在显著差异（P〈0.05）,其中地区2人员的AMS发生率显著高于地区3、4、5（P〈0.05）。地区2人员头痛发生率为82.8%,与地区3、4、5比较差异有统计学意义（P〈0.05）,乏力和嗜睡症状发生率分别为72.4%、27.6%,与地区5比较差异有统计学意义（P〈0.05）,恶心、呕吐症状发生率为37.9%,与地区3比较,差异有统计学意义（P〈0.05）。地区1和地区3人员眼花症状发生率与地区5比较差异具有统计学意义（P〈0.05）。结论不同地区人群AMS的发生存在明显医学地理差异,不同地区人群对高原的适应能力有所不同,来自低海拔地区人群的AMS症状较高海拔地区人群重。应根据人群地域差异采取有针对性的AMS防护措施。

英文摘要：

Objective To investigate the incidence of acute mountain sickness （AMS） among young men from different regions when arriving in Tibet, and explore the medical geographic differences of high altitude adaptability of people from different regions. Methods Cluster sampling survey of AMS incidence was performed among the young men from different regions when arriving in high altitude area, by using the AMS symptoms scoring method, and the military standards were employed as reference, for classifying and scoring. For distinguishing the differences of geographic environment, the systematic cluster analysis of natural geographical factors of their native places was performed and verified by nonparametric tests. The one-way ANOVA was used to analyze the differences of AMS symptom scores among young men from different regions. Results The native places of the studied subjects were divided into 5 regions by cluster analysis, and the geographic factors among the 5 regions were found to be significantly different （P〈0.01）. It was found that there were significant differences in the AMS incidence among people came from different regions （P〈0.0$）. Specifically, the AMS incidence was significantly higher （P〈0.05） in people from region 2 than in people from region 3, 4 and 5. In terms of main symptoms of AMS, the incidence of headache in people from region 2 was 82.8%, and it was significantly different （P〈0.0S） from that of those coming from regions 3, 4 and 5; the incidence of nausea and vomiting was 37.9%, and it was significantly different （P〈0.05） from that of those coming from region 3; the incidence of fatigue and drowsiness was 724.% and 27.6%, and it was significantly different （P〈0.05） from that of those coming from region S. The incidence of vertigo in people from region 1 and 3 was significantly different （P〈0.05） from that of those coming from region 5. Conclusions The significant geographic differences of AMS incidence are found to exist among people coming from differ