目的:优选β-环糊精包合香桂化浊胶囊中广藿香与肉桂中混合挥发油的工艺条件。方法:采用L(934)正交设计,以挥发油的包合率为评价指标,考察挥发油与β-环糊精比例、包合温度、搅拌时间3个因素对包合工艺的影响。结果:最佳工艺条件为挥产发。油与β-环糊精比例为1∶5(mL∶g),包合温度为60℃,搅拌时间为60min。结论:所优选的工艺方法简单、效率高,适合工业化生
OBJECTIVE: To optimize β-cyclodextrin inclusion technology of volatile oil compounds of Pogostemon cablin and Cinnamomum cassia in Xianggui huazhuo capsule. METHODS: Orthogonal design was used to investigate influence effect of the ratio of the volatile oil to β-cyclodextrin, the temperature for clathration and the duration of stirring as three factors on inclusion technology with inclusion rate of volatile oil as index. RESULTS: The optimized inclusion condition was as follows: the ratio of volatile oil to β-cyclodextrin was 1 ∶ 5(mL ∶ g), the temperature for clathration was 60 ℃,and the duration of stirring was 60 min. CONCLUSION: The optimized technology is simple, efficient, and suitable for industrial production.