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中文摘要：
目的 设计一种新型高性能血管支架，使其能够在保证足够径向刚度的前提下减小支架厚度及金属覆盖率，并具有较好的轴向柔顺性，以达到减少支架内再狭窄的目的。方法 基于对称结构孔及非对称孔结构变形能力的研究，通过数值模拟方法对支架结构进行分析设计，并利用实验方法对加工后的支架进行径向刚度及弯曲刚度的测试。结果 新的支架结构具有较高的径向刚度、较小的金属覆盖率和较好的轴向柔顺性，对减少支架内再狭窄的产生具有一定意义。结论 基于非对称孔结构的支架设计方法是有效的，并且能够借此设计出高性能的血管支架结构。
英文摘要：
Objective To design a novel high performance stent with preferable axial flexibility by using smaller strut thickness and less metal coverage which would not compromise its radial strength, so as to reduce the in-stent restenosis. Methods Based on researches about deformation properties of both the symmetric and asymmetric cell structures, the new stent structure was designed and analyzed through numerical simulation. The radial strength and bending stiffness tests were performed to evaluate the stent made by the new design. Results The proposed design possessed a higher radial strength, smaller metal coverage and good flexibility, which would be beneficial for the reduction of in-stent restenosis. Conclusions The asymmetric structure-based stent design method is effective, by which a high performance stent design can be obtained.
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