目的:对薯蓣科植物黄药子(Dioscorea bulbiferaL.)块茎进行化学成分研究.方法:95%乙醇提取物经系统溶剂萃取后,得到的氯仿萃取部分,应用硅胶柱色谱、高效液相色谱和重结晶等方法进行分离纯化,通过波谱解析进行结构鉴定.结果:从中分离得到5个化合物,根据理化性质和谱学分析鉴定为黄独乙素(diosbulbin-B,Ⅰ),β-扶桑甾醇(β-msasterol,Ⅱ),β-谷甾醇(β-sitosterol,Ⅲ),(S)5乙基-8,8-二甲基壬醛(《S)-5-Ethyl-8,8-dimethyl nonanal,Ⅳ),2,3-Dihydroxyicosanoic酸(2,3-Dihydroxyicosanoic acid,Ⅴ).结论:化合物(Ⅱ)、(Ⅳ)、(Ⅴ)为首次从黄药子中分离得到的已知化合物.
Objective:To study the chemical constituents of the rhizome of Dioscorea bulbifera L..Methods:Five compounds were isolated and purified by chromatographic column of silica gel,recrystallization and other methods.Their structures were identified by spectral analysis.Results:Five compounds were isolated from the chloroform extraction parts of Dioscorea bulbifera L.,which were diosbulbin-B(Ⅰ),β-rosasterol(Ⅱ),β-sitosterol(Ⅲ),(S)-5-Ethyl-8,8-dimethyl nonanal(Ⅳ).Conclusion:Compounds(Ⅱ),(Ⅳ),(Ⅴ) are found for the first time in Dioscorea plant.