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中文摘要：
从N-保护的手性氨基醇出发,经氧化成醛后,与手性叔丁基亚磺酰胺发生缩合反应,再经一步还原胺化合成了一系列新型手性氨基亚磺酰胺有机小分子催化剂。将其应用于N-苯基酮亚胺的不对称硅氢化反应中,以中等收率和对映选择性获得了相应的N-苯基手性胺。
英文摘要：
A series of novel organocatalysts,chiral amino sulfinamides（5a～5f）,were synthesized from N-protected chiral amino alcohol via oxidation,reacting with chiral t-butyl sulfonamide and reductive amination.5 was further applied in the asymmetric hydrosilylation of N-phenyl ketimine by HSiCl3 to give chiral N-phenyl-methylbenzyl amine in moderate yield and enantioselectivity.
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A Facile and Efficient Approach to N-Protected-beta-Sulfinylenamines via C-Sulfinylation of Enamides
One-Pot Formation of Chiral Polysubstituted 3,4-Dihydropyrans via a Novel Organocatalytic Domino Seq
Highly Enantioselective Reduction of beta-Amino Nitroolefins with a Simple N-Sulfinyl Urea as Bifunc
Bronsted-Acid-Catalyzed Asymmetric Multicomponent Reactions for the Facile Synthesis of Highly Enant
Enantioselective concomitant creation of vicinal quaternary stereogenic centers via cyclization of a
Bronsted Acid Catalyzed Dynamic Kinetic Resolution of Azlactones for the Synthesis of Aryl Glycine D
Bronsted acid-catalyzed enantioselective Friedlander condensations: achiral amine promoter plays cru
Catalytic decarboxylative alkylation of beta-keto acids with sulfonamides via the cleavage of carbon
Enantioselective Synthesis of Tetrahydropyrano[3,4-b]indoles Catalyzed by Chiral N-Triflyl Phosphora
Enantioselective Michael/Mannich Polycyclization Cascade of Indolyl Enones Catalyzed by Quinine-Deri
Enantioselective N-Heterocyclic Carbene-Catalyzed Michael Addition to alpha,beta-Unsaturated Aldehyd
Synthesis of (1R,2R)-DPEN-derived triazolium salts and their application in asymmetric intramolecula
Asymmetic Organocatalytic 1,3-Dipolar Cycloaddition of Azomethine Ylide to Methyl 2-(2-Nitrophenyl)a
Catalytic Asymmetric Pictet-Spengler-Type Reaction for the Synthesis of Optically Active Indolo[3,4-
Step-Economical Synthesis of Tetrahydroquinolines by Asymmetric Relay Catalytic Friedlander Condensa
Core-Structure-Oriented Asymmetric Organocatalytic Substitution of 3-Hydroxyoxindoles: Application i
Catalytic Asymmetric Cleavage of sp3 C-N Bonds for Access to Highly Enantioenriched N-Benzylic Sulfo
Kinetic Resolution of Racemic 2,3-Allenoates by Organocatalytic Asymmetric 1,3-Dipolar Cycloaddition
Asymmetric organocatalytic formal double-arylation of azomethines for the synthesis of highly enanti
A Highly Tunable Stereoselective Olefination of Semistabilized Triphenylphosphonium Ylides with N-Su
Byproduct-Catalyzed Four-Component Reactions of Aldehydes with Hexamethyldisilazane, Chloroformates,
Asymmetric intramolecular oxa-Michael addition of activated alpha,beta-unsaturated ketones by chiral
Highly Enantioselective Relay Catalysis in the Three-Component Reaction for Direct Construction of S
Organocatalytic Asymmetric Formal [4+2] Cycloaddition for the Synthesis of Spiro[4-cyclohexanone-1,3
The role of double hydrogen bonds in asymmetric direct aldol reactions catalyzed by amino amide deri
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Desymmetrization of Cyclohexadienones via Bronsted Acid-Catalyzed Enantioselective Oxo-Michael React
Catalytic Regioselective Synthesis of Structurally Diverse Indene Derivatives from N-Benzylic Sulfon
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Direct Assembly of Aldehydes, Amino Esters, and Anilines into Chiral Imidazolidines via Bronsted Aci
Organocatalytic asymmetric syn-aldol reactions of aldehydes with long-chain aliphatic ketones on wat
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Dual-reagent organocatalysis with a phosphine and electron-deficient alkene: application to the Henr
Organocatalytic asymmetric formal [3+2]cycloaddition reaction of isocyanoesters to nitroolefins lead
Dynamic kinetic asymmetric transfer hydrogenation of racemic 2,4-diaryl-2,3-dihydrobenzo[b][1,4]diaz
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An Expeditious Entry to Benzylic and Allylic Sulfones through Byproduct-Catalyzed Reaction of Alcoho
Stereoselective Synthesis of Polysubstituted Alkenes through a Phosphine-Mediated Three-Component Sy
N-Heterocyclic Carbene Catalyzed Ring Expansion of Formylcyclopropanes: Synthesis of 3,4-Dihydro-alp
Methyltrichlorosilane-DMSO: A Facile and Highly Efficient Recipe for the Chlorination of Enamides an
Asymmetric Synthesis of Chiral Oxazolines by Organocatalytic Cyclization of alpha-Aryl Isocyanoester
Catalyst-Free Alkylation of Sulfinic Acids with Sulfonamides via Sp(3) C-N Bond Cleavage at Room Tem
Asymmetric Construction of Polycyclic Indoles through Olefin Cross-Metathesis/Intramolecular Friedel
Enantioselective Synthesis of Fluorene Derivatives by Chiral Phosphoric Acid Catalyzed Tandem Double
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