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氟-18-脱氧葡萄糖PET/CT在胃淋巴瘤的诊断及疗效评价中的应用
  • ISSN号:1005-5185
  • 期刊名称:《中国医学影像学杂志》
  • 时间:0
  • 分类:R735.204.5[医药卫生—肿瘤;医药卫生—临床医学] R733.41[医药卫生—肿瘤;医药卫生—临床医学]
  • 作者机构:[1]南京军区南京总医院,江苏南京210002
  • 相关基金:南京军区南京总医院立项课题(编号:2011024)
中文摘要:

目的探讨氟-18-脱氧葡萄糖(18F-FDG)PET/CT在胃淋巴瘤的诊断及疗效评价中的价值。资料和方法25例经病理确诊的胃淋巴瘤,男性19例,女性6例,年龄22~79岁;分为3组,Ⅰ组11例,仅在治疗前进行1次PET/CT显像;Ⅱ组5例,治疗前、后多次PET/CT显像;Ⅲ组9例,仅在治疗后进行PET/CT显像。结果将Ⅰ组、Ⅱ组16例胃淋巴瘤患者治疗前的PET/CT影像表现分为4型,6例胃壁弥漫性增厚伴FDG代谢显著增高(Ⅰ型);7例胃壁节段性增厚伴FDG代谢显著增高(Ⅱ型);2例胃壁局限性增厚伴FDG代谢增高(Ⅲ型);1例胃壁多发结节样增厚伴FDG代谢串珠样增高(Ⅳ型)。Ⅱ组5例PET/CT评价疗效,4例达完全缓解,1例达部分缓解。ⅢⅢ组9例中有5例PET/CT显像阴性,1例发现新生肺癌,3例发现淋巴结活性病灶。结论胃淋巴瘤的18F-FDGPET/CT影像以Ⅰ型、Ⅱ型表现为主;18F-FDGPET/CT能较全面、准确地评价胃淋巴瘤的治疗效果。

英文摘要:

Purpose To explore the clinical value of 18F-FDG PET/CT in the diagnosis and therapeutic response evaluation of gastric lymphoma. Materials and Methods Twenty-five patients (19 males and 6 females, age 22~79 years) with endoscopic and surgical pathology proved gastric lymphoma were divided into three groups. Eleven patients in group I underwent PET/CT before treatment; five patients in group Ⅱ underwent PET/CT before and after treatment; nine patients in groupⅢ received PET/CT imaging only after treatment. Results In sixteen patients from groups I and Ⅱ receiving PET/CT before treatment, there were 4 types of gastric lymphoma. There were 6 with typeⅠ(diffuse thickened gastric wall with significantly high FDG uptake), 7 with type Ⅱ(segmental thickened gastric wall with significantly high FDG uptake), 2 with type Ⅲ(local thickened gastric wall with high FDG uptake) and 1 with type Ⅳ(multiple nodular thickened gastric wall with string-of-beads high FDG uptake). When evaluating therapeutic response in five patients after treatment in group Ⅱ, PET/CT showed 4 cases with complete remission and 1 case with partial remission. Of the nine patients receiving post-treatment PET/CT scan in group Ⅲ, 5 cases showed negative FDG uptake; 1 case showed high-uptake pulmonary neoplasm; 3 cases were found to have lymph nodes with high FDG uptake. Conclusions TypeⅠand type Ⅱ findings of gastric lymphoma are more often seen on PET/CT imaging. PET/CT can accurately evaluate the therapeutic response of gastric lymphoma.

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期刊信息
  • 《中国医学影像学杂志》
  • 中国科技核心期刊
  • 主管单位:中华人民共和国国家卫生和计划生育委员会
  • 主办单位:中国医学影像技术研究会
  • 主编:蔡幼铨
  • 地址:北京复兴路28号
  • 邮编:100853
  • 邮箱:zyyz@j-medicalimaging.com
  • 电话:010-66939381
  • 国际标准刊号:ISSN:1005-5185
  • 国内统一刊号:ISSN:11-3154/R
  • 邮发代号:82-712
  • 获奖情况:
  • 国内外数据库收录:
  • 被引量:18321