中文摘要：

六元环化合物是最常见的环状化合物之一，在许多天然产物和具有生物活性的化合物中存在六元环系，因此其合成方法学的研究一直受到化学工作者的重视．在众多合成方法中，[5＋1]环合策略作为一种新颖的方法的研究已越来越多，应用得到进一步拓展．结合二乙烯基酮结构特点，就其参与的[5C＋1X]成环反应最新进展做一综述．

英文摘要：

Six-membered cycle is the most common motif in the structure of natural products and bio- logically active compounds. The synthetic methodology of six-membered cycles has attracted much at- tention of chemists. Among the existing method, [5C＋1X] annulation is a novel strategy to construct six- membered ring. In this review,the new development of the [5C＋1X] annultation strategy with poly- sub stituted divinyl ketones is summarized.