目的:探讨在慢性非细菌性前列腺炎患者中检测生殖支原体感染的临床价值。方法采集医院2011年1月-2013年8月门诊及住院共计683份慢性非细菌性前列腺炎患者的前列腺液标本,作为观察组,采用聚合酶链反应(PCR)技术以及培养法检测标本中的生殖支原体是否为阳性,另采集正常的前列腺液标本287份作为对照组,用同样方法测定标本中的生殖支原体。结果在683份慢性非细菌性前列腺炎患者的前列腺液标本中,生殖支原体阳性的共有276份,阳性率40.41%;在287份正常人的前列腺液标本中,生殖支原体阳性的共有9份,阳性率3.14%,两组前列腺液标本的生殖支原体阳性率比较,差异有统计学意义( P<0.05);观察组合并有其他病原菌感染的共145例,占52.54%,其中解脲脲支原体(U u )感染102例,沙眼衣原体(C T )感染12例,人支原体(Mh)感染5例,Uu+CT感染14例,Uu+Mh感染5例,Mh+CT感染3例,Uu+CT+Mh感染4例。结论慢性非细菌性前列腺炎患者的生殖支原体感染率明显高于正常人,因此生殖支原体很可能是慢性非细菌性前列腺炎的发病原因之一。
OBJECTIVE To explore the clinical value of detection of Mycoplasma genitalium infection in patients with chronic non-bacterial prostatitis .METHODS From Jan 2011 to Aug 2013 ,totally 683 prostatic fluid specimens were collected from the patients with chronic non-bacterial prostatitis in the outpatient department and inpatient department and were set as the observation group ,then the M .genitalium was detected in the specimens by using polymerase-chain-reaction (PCR) and culture method;287 prostatic fluid specimens obtained from the healthy people were collected and set as the control group ,and the M .genitalium was detected by using the same method . RESULTS Of the 683 prostatic fluid specimens obtained from the patients with chronic non-bacterial prostatitis , 276 were detected positive for the M .genitalium ,with the positive rate of 40 .41% ;9 of 287 prostatic fluid speci-mens obtained from the healthy people were tested positive for the M .genitalium , with the positive rate of 3 .14% ,and there was significant difference in the positive rate of M .genitalium between the two groups of pros-tatic fluid specimens (P<0 .05) .Totally 145 (52 .54% ) patients in the observation group were complicated with infections caused by other species of pathogens ,including 102 cases of Uu infection ,12 cases of CT infection ,5 cases of Mh infection ,14 cases of mixed Uu with CT infection ,5 cases of mixed Uu with Mh infection ,3 cases of mixed Mh with CT infection ,and 4 cases of mixed Uu ,CT ,with Mh infection .CONCLUSION The incidence of M .genitalium infection is significantly higher in the patients with chronic non-bacterial prostatitis than in the healthy people ,thus ,the M .genitalium may be one of the leading causes of the chronic non-bacterial prostatitis .