目的:研究接骨木根皮(roots of Sambucus williamsii Hance)的化学成分。方法:采用反复的柱色谱和HPLC等分离手段,对接骨木根皮乙醇提取物进行分离,并通过核磁共振谱和质谱等波谱数据对其结构进行鉴定。结果与结论:从接骨木根皮中分离得到6个化合物,分别鉴定为α-莫诺苷(α-morroniside,1),β-莫诺苷(β-morroniside,2),山栀子苷A(Caryoptoside,3),(7S,8R)-4,9,9’-三羟基-3,3’-二甲氧基-7,8-二氢苯骈呋喃-1’-丙醇基新木脂素((7S,8R)-4,9,9’-trihydroxy-3,3’-dimethoxy-7,8-dihydrobenzofuran-1’-propanolneolignan,4),Ligstroside(5),β-谷甾醇(6)。
Objective: To study the chemical constituents from roots of Sambucus williamsii Hance. Methods: The chemical constituents of Sambucus williamsii Hance were isolated and purified by repeated column chromatography and preparative HPLC. Their structures were elucidated on the basis of ESI-MS and NMR spectra. Results and Conclusion: Six compounds were isolated. They were identified as α-morroniside( 1),β-morroniside( 2),Caryoptoside( 3),( 7S,8R)-4,9,9’-trihydroxy-3,3’-dimethoxy-7,8-dihydrobenzofuran-1’-propanolneolignan( 4),Ligstroside( 5),β-sitosterol( 6).