超声热疗在临床上得到了越来越广泛的应用,成为目前临床治疗的一种有效手段,但治疗中人体组织的温度测量是决定治疗成败的重要因素。基于超声的温度分布的无损测量是其中的一种方案,也成为医学超声研究的一个热点。采用有限差分的离散方法求解Pennes方程,从而得到了超声作为热源的情况下双层生物组织中的温度场。通过实验验证,说明该方法能较为准确地计算出超声热源情况下双层组织中的温升分布情况。同时讨论了各个参数对双层组织温度的影响,实验和计算结果发现初始声压和组织的热传导率对焦点温升的影响较大,组织的热容对焦点温升的影响很小,只有热传导率对焦点的位置有较大的影响。
Hyperthermia with ultrasound is widely used in clinical treatment. The effect of hyperthermia depends much on the measurement of the temperature in human tissues. The noninvasive temperature measurement based on ultrasound is one focus in the study of medical ultrasound. Finite-difference implementation of the Pennes equation was employed to study the temperature rise induced by ultrasound in two-layer biological tissues. The experiments showed that this method can properly obtain the temperature elevation in such tissues. We also discussed the impact of different parameters on temperature rise distribution. The experimental and calculated results showed the influence of initial pressure and thermal conductivity of tissue on the temperature rise was great while the influence of thermal capacity on the temperature rise is small. And the thermal conductivity had great effect on the position of the focus.