阿尔茨海默病(AD)属于中医老年呆病范畴,该病的西医学发病机制仍在探索中,尚无有效的治疗药物。中医认为年老,气血阴阳亏虚、脏腑功能减退是AD发病的根本原因,该病基本病机为肾虚髓空、痰瘀阻滞脑窍,临床所见证型以肾精亏虚证兼夹痰浊阻窍、瘀血阻络证为主,但具体证型随患者的年龄、体质等因素又各有差异,因此现有的辨证分型标准不能全部概括临床所见患者的证型。
Alzheimer's disease(AD) belongs to senile dementia in traditional Chinese medicine. The pathogenesis is still un- clear and there is no effective therapy to inhibit the progression of AD. In the opinion of traditional Chinese medicine, basic patho- genesis of AD is related to deficiency of kidney and marrow brain, turbid phlegm and blood stasis. Main types of syndromes in- clude deficiel-cy of kidney essence, turbid phlegm blocking the clear orifices and obstruction of collaterals by blood stasis. But with the difference of age, constitution and so on, the clinic syndrome is distinct. Therefore, the standard that we now have cannot sum- marize all clinical types.