中文摘要：

搭建基于光谱光学相干层析术(SDOCT,spectral domain optical coherence tomography)的内窥成像系统,分析SDOCT的理论分辨率和探测深度。根据近轴子午光线方程,利用矩阵法分析自聚焦GRIN(gradient index)透镜成像原理,设计适用于SDOCT扫描探头的GRIN透镜,聚焦距离为10mm,透镜长度为5.31mm,直径为1.8mm。通过光学传递函数(MTF)对比GRIN透镜和传统球面透镜对成像质量的影响。利用内窥成像系统对洋葱内外表皮样品进行成像,获得3.2mm×0.7mm的层析图像。实验结果表明,利用GRIN透镜聚焦光束时,SDOCT系统的横向分辨率可达8μm,成像质量得到提高。

英文摘要：

Endoscope imaging system based on spectral domain optical coherence tomography(SDOCT)is developed.Its theoretical resolutions and imaging depth are studied.According to the paraxial meridian line equation,the imaging principle of self-focusing(Gradient Index,GRIN)lens is discussed.GRIN lens whose length is 5.31 mm and diameter is 1.8 mm is designed for SDOCT scanning probe.By use of modulating transfer function,the effect of GRIN lens on imaging quality is contrasted with traditional sphere lens.By use of e...