中文摘要：

合成了Ⅳ-[（R）-a-叔丁氧基羰基苄基]甲基丙烯酰胺（（R）-BCBMAM），通过自由基聚合法获得相应的光学活性聚合物（P（R—BCBMAM）），并以三氟乙酸为水解催化剂除去叔丁基而得到（P（R·CBMAM））．用1H-NMR，IR，CD和GPC对聚合物进行了结构表征，发现聚合溶剂和聚合物分子量对所得聚合物P（尺一BCBMAM）的光学活性没有明显影响，P（R-BCBMAM）水解后光学活性有较大的改变．与单体相比，聚合物的比旋光度有较大的区别，且在对应于其侧基的紫外吸收处呈现明显不同于单体的Cotton效应，说明聚合物的主链可能形成了一定的二级结构．以P（R—BCBMAM）和P（R—CBMAM）制备的2种涂敷型高效液相色谱用手性固定相，对部分对映体具有一定的手性拆分能力．利用’H—NMR技术研究了上述2种聚合物与1，1’-联-2·萘酚（BINOL）的相互作用，它们对BINOL都具有良好的手性识别能力．

英文摘要：

A chiral monomer N-[ （ R）-a-tert-butoxycarbonylbenzyl] methacrylamide （ （R） -BCBMAM） was synthesized via amidation reaction between methacryloyl chloride and D-phenylglycine tert-butyl ester. Optically active polymers were prepared via free radical polymerization of （（R） -BCBMAM） initiated by AIBN at 60 ℃. In the presence of catalytic amount of trifluoroacetic acid, the tert-butyl of P （R-BCBMAM） was removed to obtain poly （ N- [ （R） -a-hydroxylcarbonylbenzyl ] methacrylamide t P （ R-CBMAM ）. ＇ H-NMR, IR, CD and GPC were employmed to characterize the chemical structure of the products. The results indicated that the polymerization condition had slight effects on the chiroptical properties of P （R-BCBMAM）. The results from specific optical rotation and circular dichroism spectra indicated that the P（R-CBMAM） and P（R-BCBMAM） had great difference in the chiroptical properties. On the basis of the results from circular dichroism （CD） ,the optical activity of P （R-BCBMAM） was attributed not only to the chirality of amino acid side groups in monomeric units but also to the steric repulsion of tert-butyl groups. P（R-BCBMAM） and P（R-CBMAM） were coated onto silica gels as the chiral stationary phase （CSP） for high performance liquid chromatography （ HPLC）. The CSPs exhibit superior chiral recognition ability for some racemates. On the other hand,＇ H-NMR measurements of mixture of polymers and racemic 1,1 ＇-bi-2-naphthol （BINOL） were conducted in chloroform- d. The characteristic hydroxyl proton signal of BINOL was split into two peaks ascribed respectively to the levo- and dextro-isomers.