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Relationship between high-sensitivity C-reactive protein level and angiographical characteristics of coronary atherosclerosis
  • ISSN号:0366-6999
  • 期刊名称:《中华医学杂志:英文版》
  • 时间:0
  • 分类:R543.5[医药卫生—心血管疾病;医药卫生—临床医学;医药卫生—内科学]
  • 作者机构:[1]Department of Cardiovascular Medicine, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China, [2]Department of Chest Surgery, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China, [3]Department of Clinical Laboratory, First affiliated hospital of Nanjing Medical University, Nanjing 210029, China
  • 相关基金:This study was supported by a grant from the National Natural Science Foundation of China (No.30400173).
中文摘要:

为发炎的一个角色变得很好在描述动脉粥样硬化患者疾病过程的理论在过去的十年或更多建立了。从一个病理学的观点,都上演,即,动脉粥样硬化患者匾的开始,生长,和复杂并发症,可能被认为是对损害的煽动性的回答。几未来的研究最近高显示出那血浆 C 反应的蛋白质(hsCRP ) 铺平的敏感,是全身的发炎的标记之一,是未来的一个强大的预言者在显然健康的个人之中的心肌的梗塞和心脏的死亡。然而,在血浆 hsCRP 层次之间的协会和在题目的冠的狭窄的程度仍然保持争论。一些研究以前表明了如此的协会,而其它不能发现。Gensini “ s 分数为取决于钠变窄和它的地点的重要性的度的一个患狭窄症的容器分配一个严厉分数。

英文摘要:

A role for inflammation has become well established over the past decade or more in theories describing the atherosclerotic disease process. From a pathological viewpoint, all stages, ie, initiation, growth, and complication of the atherosclerotic plaque, might be considered to be an inflammatory response to injury. Several prospective studies recently showed that plasma high sensitivity C-reactive protein (hsCRP) levels, which are one of the markers of systemic inflammation, are a powerful predictor of future myocardial infarction and cardiac death among apparently healthy individuals. However, the association between the plasma hsCRP levels and the extent of coronary stenosis in subjects remains controversial. Some studies previously demonstrated such associations, whereas other could not found. Gensini's score assigns a severity score for a stenosed vessel depending on the degree of luminal narrowing and the importance of its location.

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期刊信息
  • 《中华医学杂志:英文版》
  • 中国科技核心期刊
  • 主管单位:中国科协
  • 主办单位:中华医学会
  • 主编:
  • 地址:北京东四西大街四十二号
  • 邮编:100710
  • 邮箱:cmj@cma.org.cn
  • 电话:010-85158321
  • 国际标准刊号:ISSN:0366-6999
  • 国内统一刊号:ISSN:11-2154/R
  • 邮发代号:2-920
  • 获奖情况:
  • 1997、1998、1999年获中国科协优秀科技期刊择优资...,1992、1997年连续两年荣获全国优秀科技期刊和中国...,中国期刊方阵双高期刊
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  • 美国化学文摘(网络版),英国农业与生物科学研究中心文摘,荷兰文摘与引文数据库,荷兰医学文摘,美国生物医学检索系统,美国科学引文索引(扩展库),美国生物科学数据库,日本日本科学技术振兴机构数据库,中国中国科技核心期刊
  • 被引量:3319