中文摘要：

目的：针刺腰骶段穴位对不稳定膀胱有调节作用。本研究拟确定针刺会阳穴治疗不稳定膀胱的尿动力学特征及时效性，为经穴脏腑相关理论及针刺作用规律提供科学依据。方法：将80Wistar大鼠造成不稳定膀胱模型，随机分为模型组和治疗组，每组40只。每组再根据针刺后2h、6h、12h和24h不同观察节点分为4小组，给予相应处理，并进行尿动力学测定。分析针刺会阳穴对不稳定膀胱进行调节的动态尿动力学特征。结果：针刺会阳穴后2h、6h和12h分组观察，治疗组在各节点膀胱顺应性改善明显优于模型组（P〈0．05），且治疗组在针刺后2h、12h节点膀胱容量增加量明显优于模型组（P〈0．05）；针刺会阳穴后，在不同的时间节点不稳定膀胱的尿动力学改善程度有差异，其中在针刺后12h时，膀胱的顺应性提高程度和膀胱容量的增加量较为明显（P〈0．05），在针刺24h后尿动力的改善效应下降。结论：针刺会阳穴可改善不稳定膀胱尿动力状态，提高膀胱顺应性，增加膀胱容量；针刺会阳穴对不稳定膀胱尿动力状态的调节存在时效性，其中以针刺会阳穴后12h调节效应最显著。

英文摘要：

Objective： Needling lumbosacral acupoints could regulate unstable bladder （USB）. The present study is to observe the ambulatory urodynamics changing of needling Huiyang （BL 35） on USB to provide scientific basis for the relative theory of acupoint and Zang-fu organs, and the rule of acupuncture treatment. Methods： Unstable bladder model were prepared in 80 Wistar rats, and then they were randomly divided into treatment group （n=40） and model group （n=40）. The urodynamics were monitored respectively at 2 h, 6 h, 12 h and 24 h after acupuncture and the results were analyzed. Results： After acupuncture Huiyang （BL 35）, the compliance of bladder were superior to that of model group at 2 h, 6 h and 12 h, respectively （P〈0.05）, and the bladder volume were superior to that of model group at 2 h and 12 h, respectively （P〈0.05）. After acupuncture Huiyang （BL 35）, the compliance and volumn of bladder at 12 h were superior to those at other time （P〈0.05）. Twenty-four hours later, the effect of acupuncture on urodynamics decreased. Conclusion： Needling Huiyang （BL 35） could improve the urodynamics of USB, including improving the compliance of bladder and increasing the volume of bladder. Acupuncture Huiyang （BL 35） had the most effect at 12 h.