勃起功能障碍(ED)是糖尿病进程中常见的并发症,其发病机制十分复杂,涉及到神经及神经递质、血管及血管活性物质、内分泌、代谢等多方面因素。糖尿病状态下,自由基增多引发氧化应激损伤,影响到糖尿病性ED发生发展中的各个环节。本文针对氧化应激在糖尿病性勃起功能障碍进程中的作用作一综述。
Erectile dysfunction is a common complication of diabetes mellitus,and the pathogenesis of diabetic erectile dysfunction is very complicated,involving neuropathy,neurotransmitters,vasculopathy,vasoactive mediators,metabolism,endocrine and so on.Diabetes mellitus can cause oxidative stress,which plays an important role in the pathogenesis of diabetic complications.This review aims at the role of oxidative stress in the pathogenesis of diabetic erectile dysfunction.