支气管哮喘(简称哮喘)是最常见的儿童慢性呼吸道疾病,其发病是个体遗传易感性和环境过敏原暴露之间相互作用的结果。我国儿童哮喘患病率逐年增加,从1990年的0.91%增长到2000年的1.54%。而由于其致病因素复杂性和临床表型多样性,其发病机制尚不完全明确。随着研究的深入,调节性T细胞在儿童哮喘治疗中的调节功能以及在特异性免疫治疗过程中发挥重要的免疫抑制作用逐渐得到人们的重视。
Bronchial asthma (asthma) is the most common chronic airway disease of children, which is caused by the relationship between the personal genetic sensitization and the exposure to environmental allergens. The prevalence of chinese pediatric asthma is increasing,ranging from 0.91 % of 1990 to 1.54% of 2000. Due to its complexity of pathogenic factors and the diversity of the clinical types, the pathogenesis of asthma is not totally known. With the deepening of the research, T regulatory cells have got more attention for its regulatory function in the treatment of pediatric asthma and the immune inhibition function in the specific immunotherapy.