位置：成果数据库 > 期刊 > 期刊详情页
Yhhu3813 is a novel selective inhibitor of c-Met kinase that inhibits c-Met-dependent neoplastic phenotypes of human cancer cells
  • ISSN号：1671-4083
  • 期刊名称：《中国药理学报：英文版》
  • 分类：Q55[生物学—生物化学] TQ463.54[化学工程—制药化工]
  • 作者机构：[1]Division of Anti-tumor Pharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China, [2]State Key Laboratory of Drug Research, Department of Medicinal Chemistry, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China
  • 相关基金：Acknowledgements This work was supported by funds from the National Program on Key Basic Research Project of China （No 2012CB910704）, the Natural Science Foundation of China for Innovation Research Group （No 81021062）, the National Natural Science Foundation of China （No 81102461）, and the National S＆T Major Projects （2012ZX09301001-007）.
作者： Chang-xi HE[1], Jing AI[1], Wei-qiang XING[2], Yi CHEN[1], Hao-tian ZHANG[1], Min HUANG[1], You-hong HU[2], Jian DING[1], Mei-yu GENG[1]
关键词： 选择性抑制剂, 抗肿瘤特性, 激酶活性, 癌细胞, 依赖性, 人类, 表型, Western印迹, human cancer, anticancer drug, Yhhu3813, c-Met, receptor tyrosine kinase, xenograft nude mouse model
中文摘要：

To whom correspondence should be addressed. E-mail mygeng@simm.ac.cn

同期刊论文项目
靶向c-Met抑制剂药效监控标志物的发现研究
期刊论文 19
同项目期刊论文
Yhhu3813 is a novel selective inhibitor of c-Met kinase that inhibits c-Met-dependent neoplasti
Design and synthesis of 3,3'-biscoumarin-based c-Met inhibitors.
Discovery of Anilinopyrimidines as Dual Inhibitors of c-Met and VEGFR-2: Synthesis, SAR, and Ce
O-Linked Triazolotriazines: Potent and Selective c-Met Inhibitors.
Discovery of Novel 2,4-Diarylaminopyrimidine Analogues (DAAPalogues) Showing Potent Inhibitory
SOMCL-863, a novel, selective and orally bioavailable small-molecule c-Met inhibitor, exhibits
Synthesis and biological evaluation of 2 - amino - 5 - aryl - 3 - benzylthiopyridine scaffold based
Investigation on the 1,6-naphthyridine motif: discovery and SAR study of 1H-imidazo[4,5-h][1,6]napht
SOMG-833, a novel selective c-MET inhibitor, blocks c-MET-dependent neoplastic effects and exer
Discovery of novel type II c-Met inhibitors based on BMS-777607.
Novel 2,4-Diarylaminopyrimidine Analogues (DAAPalogues) Showing Potent c-Met/ALK Multikinase I
Yhhu3813 is a novel selective inhibitor of c - Met Kinase that inhibits c - Met - dependent neoplast
期刊信息
  • 《中国药理学报：英文版》
  • 中国科技核心期刊
  • 主管单位:中国科学技术协会
  • 主办单位:中科院上海药物研究所
  • 主编：丁光生
  • 地址：上海市太原路294号31号楼
  • 邮编：200031
  • 邮箱：
  • 电话：021-54922821 54922822
  • 国际标准刊号：ISSN：1671-4083
  • 国内统一刊号：ISSN：31-1347/R
  • 邮发代号:4-295
  • 获奖情况:
  • 1992、1996年两届全国优秀科技期刊一等奖,1992、1996、1997年中国科协、中科院以及上海市优...,首届国家期刊奖、2000年中科院优秀期刊评比特别奖
  • 国内外数据库收录:
  • 俄罗斯文摘杂志,美国化学文摘（网络版）,英国农业与生物科学研究中心文摘,波兰哥白尼索引,荷兰文摘与引文数据库,荷兰医学文摘,美国生物医学检索系统,美国剑桥科学文摘,美国科学引文索引（扩展库）,美国生物科学数据库,日本日本科学技术振兴机构数据库,中国中国科技核心期刊,英国食品科技文摘,中国北大核心期刊（2000版）
  • 被引量:1239