目的:探讨加味麻杏石甘汤配合穴位贴敷对AECOPD肺功能、炎症因子和生活质量的影响。方法:选择2015年1月-2016年12月本院受疗的90例AECOPD患者为研究对象,按照随机数字表法分为对照组和治疗组,对照组采用穴位贴敷治疗,治疗组采用加味麻杏石甘汤配合药物穴位贴敷,治疗2周后,观察两组患者的临床疗效、肺功能、炎性因子及患者的生活质量。结果:治疗组的总有效率为93.75%,显著高于对照组的79.19%,差异有统计学意义(P〈O.05)。治疗后治疗组和对照组的肺功能均较治疗前提高,治疗组的好转幅度大于对照组,具有统计学意义(P〈0.05)。治疗后两组患者的血清TNF-α、PCT、IL-8均低于治疗前,且治疗组的低于对照组,差异有统计学意义(P〈0.05)。治疗后两组患者的情绪功能、认知功能、角色功能、躯体功能、社会功能等生活质量评分均高于治疗前,且观察组优于对照组,差异均有统计学意义(P〈0.05)。结论:加味麻杏石甘汤配合穴位贴敷可提高AECOPD患者的临床疗效,改善患者的肺功能,降低炎症因子表达,提高患者的生活质量。
Objective : To analyze the influence of Modified Maxing Shigan Decoction on lung function, inflammatory factors and quality of life of AECOPD patients. Methods : In our hospital during January 2015 to December 2016,90 cases of AECOPD patients were selected as the subjects and divided randomly into the control group and treatment group. The control group used the acu- points application and the treatment group used the Modified Maxing Shigan Decoction. After 2 weeks treatment, the clinical effect,lung function, inflammatory factos and quality of life were observed and compared between two groups. Results : The total ef- fective rate was 93.75% in the treatment group and significantly higher than 79.19% in the control group. The difference was significant (P 〈 0. 05 ). After treatment,the lung function in two groups were both increased and the improvement in the treatment group was better than that of the control group(P 〈 0. 05 ). The two groups' TNF - α,PCT and IL - 8 were both lower than those before treatment and the treatment group's were lower than that of the control group ( P 〈 0. 05 ) ; After treatment, the quality of life including emotions ,cognition,social functions and so on was higher and the treament group's was superior to that of the control group(P 〈0. 05). Conclusion:Modified Maxing Shigan Decoction and acupoints application can increase the clinical effect, im- prove the lung function,decrease the inflammatory factors expressions and increase the quality of life of AECOPD patients.