中文摘要：

目的：调查丁丙诺啡（buprenorphine,Bup）在吸毒人群中滥用/使用的一般情况,评价其药物滥用与药物依赖性潜力。方法：自拟调查表,采取回顾性调查方法,于2006年1月-2006年7月在北京、云南、湖北和广东四地区的六所公安、司法强制戒毒机构,以戒毒所为单位,对符合调查对象条件的全体戒毒人员进行整群调查。结果：（1）使用率：在3254例被调查者中,27.4%（892例）不同程度、不同目的使用过Bup。使用率以云南个旧最高,北京地区次之。（2）使用目的及场所：用于＂戒毒或临时替代＂及＂治疗戒毒后稽延性症状＂分别占55.8%和40.6%;82例（9.2%）为＂体验特殊精神效应（如欣快、飘等）＂。使用场所：主要是在＂自己家中＂（74.4%）和＂戒毒所＂（32.1%）。（3）使用方式：47.7%的人有多药使用的经历。在有多药使用者中,采用Bup加镇静催眠药（三唑仑、安定）、氯丙嗪、东莨菪碱和异丙嗪分别占47.6%、5.8%、1.2%和10.1%。（4）使用频率：连续3 d以上使用经历者占36.1%,偶尔使用/间断使用占34.3%,有时连续、有时间断使用占29.5%。（5）主要来源：＂医院或诊所＂、＂戒毒机构＂（或在戒毒机构中使用）、＂药店＂、＂非正常渠道＂（黑市）、＂亲朋＂分别占24.7%、38.7%、29.0%、18.4%,4.9%。（6）获得的难易程度：34.0%表示很容易得到,23.4%表示比较容易得到,12.5%表示比较困难得到,7.2%表示非常困难得到,22.8%表示不知道或不便回答。（7）使用后的感觉：46.0%应答者主诉使用后＂有感觉＂,其中＂快感＂占33.8%,＂幻觉＂占26.6%,＂飘感＂占34.8%。这种特殊感觉＂同海洛因不一样＂占67.6%;＂同海洛因一样,但比海洛因作用小＂占25.8%;＂同海洛因一样,但比海洛因作用强＂占4.5%。以上主观效应是单一使用丁丙诺啡产生的占63.8%,合并用药产生的占36.2%。结论：本次调查有近30%的?

英文摘要：

Objective ：To understand the basic situation of buprenorphine abuse/use in drug users and assess its dependence and abuse potential liability. Methods： Buprenorphine users who met our investigation criteria were totally interviewed by retrospective survey with self- designed questionnaire in 6 compulsory detoxifieation units of 4 provinces （ Beijing, Yunnan, Hubei and Guangdong） from January to July in 2006. Results ： （ 1 ） Use rate： 27.4% （ 892 eases） ever used buprenorphine in different degrees and for different purposes. The use rate of Gejiu of Yunnan was the highest, then Beijing. （2） Purposes and places ： the main purpose was ＂detoxification or temporary replacement＂ （ 55.8% ） and＂ protracted abstinence treatment＂ （40. 6% ）. 82（9.2% ） were seeking for special effect such as euphoria. The main places for using were at home （74.4%） and detoxification units（32. 1% ）. （3） Routes： 47.7% were polydrug users. Buprenorphine used with sedative/hypnotic, chlorpromazine, scopolamine and fenazil were 47.6% , 5.8%, 1.2% and 10. 1%, respectively. （4） Frequency： continuous use, un - continuous use and sometimes continuous, sometimes un - continuous use were 36. 1%, 34. 3%, and 29. 5%, respectively. （5） Source ： clinics, detoxification agents, drug store, black market, relative/ friends, others were 24. 7%, 38.7% , 29. 0% , 18.4% and 4. 9%, respectively. （ 6 ） Availability： 34. 0% obtained very easily, 23. 4% easily, 12.5% difficuldy, 7. 2% very difficuldy, and 22. 8% did not know or answer. （7） Feelings： 46.0% had feelings after using buprenorphine. Euphoria, hallucination and float accounted for 33.8%, 26. 6% and 34. 8%, respectively. 67.6% feelings were different from heroin, 25.8% were less than heroin, 4. 5% were stronger than heroin. 63.8% happened by itself and 36.2% happened by ploy - drug. Conclusion： In drug users population, about 30% used buprenorphine in different degrees and for different purposes. Main purpose is for medica