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云南省德宏州少数民族村寨居民丙型肝炎病毒感染及其影响因素
  • ISSN号:1009-6639
  • 期刊名称:中国预防医学杂志
  • 时间:2012.11.11
  • 页码:801-804
  • 分类:R181.3[医药卫生—流行病学;医药卫生—公共卫生与预防医学]
  • 作者机构:[1]复旦大学公共卫生学院流行病学教研室、公共卫生安全教育部重点实验室,上海200032, [2]云南德宏州疾病预防控制中心, [3]陇川县疾病预防控制中心, [4]苏州市疾病预防控制中心
  • 相关基金:国家自然科学基金资助(81072345)
  • 相关项目:HIV感染者配偶艾滋病队列研究
中文摘要:

目的了解云南省德宏州少数民族村寨居民丙型肝炎病毒(HCV)感染状况及其影响因素。方法采用横断面研究方法,从德宏州整群抽样10个相邻的少数民族村寨,所有16岁及以上居民为研究对象,问卷调查收集社会人口学、性行为和吸毒行为信息,并采集外周静脉血检测HCV抗体。对研究对象的基本情况采用描述性分析,对分类计数变量关联性采用χ2检验,并应用logistic回归分析HCV感染的影响因素,P〈0.05为差异有统计学意义。结果本项研究共有735人符合入选标准,参与应答者582人,占79.18%。其中男性306人,占52.58%;年龄16~56岁,平均(34.55±10.17)岁;景颇族364人,占62.54%;农民569人,占97.77%;已婚491人,占84.36%。543人有过性行为,占93.30%;109人吸毒,占18.73%。HCV抗体阳性25人,占4.30%。多因素logistic回归分析显示,景颇族HCV感染风险高于其他民族(OR=3.69,95%CI:1.03~13.14),吸毒者HCV感染风险高于非吸毒者(OR=3.58,95%CI:1.17~10.97)。结论云南省德宏州少数民族村寨居民特别是景颇族、吸毒者HCV感染率较高,有必要加强HCV防控。

英文摘要:

Objective To understand the prevalence and correlation of hepatitis C virus (HCV) infection among minority villagers in Dehong prefecture, Yunnan province. Methods A cross-sectional survey was conducted among all permanent residents aged 16 years and above in ten villages selected by cluster sampling from Debong prefecture in Yunnan province. Participants were interviewed for their ethnicity, sexual behavior, and drug use. Blood samples were collected for HCV antibody detection by ELISA. Descriptive analysis was used to de- scribe the general information, Chi-squared test and multiple logistic regression analysis were used to determine the correlation of variables. Results Out of 735 residents who met the criteria, 582 (79.18%) individuals with age ranging from 16 to 56 (34.55±10.17 years) were eventually enrolled into the study. There were 306 (52.58%) males, and 364 (62.54%) participants were Jingpo minority; 569 (97.77%) were farmer and 491 (84.36%) were married. 543 (93.30%) individuals had sexual experience and 109 (18.73% were drug us- ers. The overall prevalence of anti HCV was found to be 4.30% (25/582) . Multiple logistic regression analy sis indicated that Jingpo minority (OR=3.69, 95% CI: 1.03-13.14) and drug users (OR=3.58, 95% CI: 1. 17-10.97) were more likely to be infected with HCV than other ethnicities and non-drug users. ConclusionsHCV prevalence was relatively high among local residents particularly Jingpo population and drug users in eth nic minority villages in Dehong prefecture, Yunnan province, underscoring the importance of enhanced efforts for HCV prevention and control.

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期刊信息
  • 《中国预防医学杂志》
  • 中国科技核心期刊
  • 主管单位:中华人民共和国卫生和计划生育委员会
  • 主办单位:中华预防医学会
  • 主编:
  • 地址:北京市朝阳区潘家园华威里25号5层
  • 邮编:100021
  • 邮箱:zgyfyxzz@163.com
  • 电话:010-84035601
  • 国际标准刊号:ISSN:1009-6639
  • 国内统一刊号:ISSN:11-4529/R
  • 邮发代号:2-764
  • 获奖情况:
  • 国内外数据库收录:
  • 被引量:14584