中文摘要：

与到 ScCdc42 (在 Saccharomyces cerevisiae 的 Cdc42 ) 的高相同， MgCdc42 (在 Magnaporthe grisea 的 Cdc42 ) 被表明了在形态发生和感染过程包含。为了推进，理解发信号的网络，通常认为的交往 MgCdc42 蛋白质被分析。交往 ScCdc42 蛋白质序列首先对 M 习惯于强风。grisea 染色体数据库将检索他们的相应类似物。随后，保存了这些蛋白质的域被比较，他们处于不同 MgCdc42 变化状态的编码基因的表达式模式被半分析量的 RT-PCR。从 M 的交往 ScCdc42 蛋白质的所有检索类似物。grisea 数据库在 S 作为那些保存了领域。cerevisiae。他们的编码基因的表示在在 MgCdc42KO 异种变异、减少的 MgCdc42CA 增加了。然而，在 MgCdc42DN 异种的 MgBeml， Chml，和 MgGicl 有在野生型，尽管 MgBem4， MgBoi2， MgCdc24， MgGic2， MgRgal，和 Mst20 减少了，表示铺平，，，这期望的一样的表示水平。总的来说，可以在那里存在，这被结束在 M 的一条类似的 Cdc42 信号小径。grisea 是在 S。cerevisiae 和 MgCdc42 在小径起一个关键作用。

英文摘要：

MgCdc42 （Cdc42 in Magnaporthe grisea）, with high homology to ScCdc42 （Cdc42 in Saccharomyces cerevisiae）, has been demonstrated to involve in the morphogenesis and infection process. To further understand the signaling network, the putative MgCdc42-interacting proteins were analyzed. ScCdc42-interacting protein sequences were first used to BLAST against the M. grisea genome database to retrieve their corresponding analogs. Subsequently, conserved domains of these proteins were compared and expression patterns of their encoding genes in different MgCdc42 mutation states were analyzed by semiquantitative RT-PCR. All retrieved analogs of ScCdc42-interacting proteins from the M. grisea database have conserved domains as those in S. cerevisiae. Expression of their encoding genes increased in MgCdc42CA mutant and decreased in MgCdc42KO mutant. However, MgBeml, Chin1, and MgGicl in MgCdc42DN mutant had the same expression level as that in the wild type, although MgBem4, MgBoi2, MgCdc24, MgGic2, MgRgal, and Mst20 had decreased expression level, as expected. Overall, it is concluded that there may exist a similar Cdc42 signal pathway in M. grisea as in S. cerevisiae and MgCdc42 plays a key role in the pathway.