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Study on the Three-dimensional Quantitative Structure-activity Relationship of Pyridazinonyl-substituted 1,3,4-Thiadiazoles

ISSN号：1001-604X
期刊名称：《中国化学：英文版》
时间：0
分类：O626[理学—有机化学;理学—化学]
作者机构：State Key Laboratory of Elemento-Organic Chemistry, Institute of Elemento-Organic Chemistry, Nankai University, Tianjin 300071, China, China
相关基金：Project (No. 29832050) supported by the National Natural Science Foundation of China.

作者：邹霞娟[1,2], 来鲁华[1], 金桂玉[3]

关键词： 5-(, Substituted-pyrazol-5’-yl, )-1, 3, 4-thiadiazole, 5-(, substituted-pyrazol-5’-yl)-1, 2, 4-triazole, 5-(, substituted-pyra-zol-5’-yl)-1, 3, 4-oxadiazole, FUNGICIDAL, ACTIVITY, PGR, ACTIVITY, 5-(Substituted-pyrazol-5′-yl)-1, 3,4-thiadiazole, 5-(substituted-pyrazol-5′-yl)-l,2,4-triazole, 5-(substituted-pyrazol-5′-yl)-1,3,4-oxadiazole, fungicidal activity, PGR activity

中文摘要：

In order to search for novel fungicides with high activity, a series of heteroaryl pyrazoles were synthesized from 5-pyra-zole formhydrazide. The structures of all new compounds were confirmed by spectroscopic methods and microanalyses. Preliminary bioassays indicated that some compounds showed fungicidal activity against Puccinia tritinia and PGR activity as well.

英文摘要：

In order to search for novel fungicides with high activity, a series of heteroaryl pyrazoles were synthesized from 5-pyrazole formhydrazide. The structures of all new compounds were confirmed by spectroscopic methods and microanalyses. Preliminary bioassays indicated that some compounds showed fungicidal activity against Puccinia tritinia and PGR activity as well.

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