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中文摘要：
以（2S，3S）-1，2-环氧基-3-叔丁氧酰胺基4-苯丁烷为原料，经过异丁基胺化、N-对硝基苯磺酰化、还原、脱保护后再与（S）-3-羟基四氢呋喃-琥珀酰亚胺基碳酸酯（7）缩合制得安普那韦，总收率73％，其结构经^1H NMR和MS确证。
英文摘要：
Amprenavir in overall yield of 73% was obtained from （2S,3S）-3-（t-butoxy）-amido-1,2- epoxy-4-phenylbutane via isobutylamination, N-4-nitrobenzene sulfonylation, reduction, deprotection, and then condensation with 7. The structure was confirmed by ^1H NMR and MS.
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