中文摘要：

[目的]分析延边地区朝鲜族和汉族小学生体质量指数（BMI）与重要脂肪细胞因子的相关性.[方法]于2011年7月—2012年7月间抽取延边地区3 879名小学生（朝鲜族2 011名,汉族1 868名）作为研究对象,测量身高和体质量,测定清晨空腹脂联素（ADP）、瘦素（LEP）及肿瘤坏死因子-α（TNF-α）水平.[结果]延边地区朝鲜族小学生BMI和LEP平均水平均显著高于汉族小学生（FBMI=121.07,FLEP=90.35,P〈0.001）;汉族小学生ADP平均水平显著高于朝鲜族小学生（FADP=89.64,P〈0.001）.延边地区小学生LEP和TNF-α平均水平均随BMI水平增高而升高,且升高趋势显著（FLEP=1 003.39,FTNF-α=14.55,P〈0.001）;延边地区小学生ADP平均水平随BMI水平增高而降低,且降低趋势显著（FADP=66.27,P〈0.001）.Spearman相关分析结果显示,延边地区小学生BMI与LEP和TNF-α水平呈正相关（r=0.428和0.130,P〈0.01）,与ADP呈负相关（r=-0.195,P〈0.01）;调整年龄、性别、民族和生物化学指标的偏相关分析结果显示,延边地区小学生BMI与ADP水平呈负相关（r=-0.149）,与LEP（r=0.572）和TNF-α（r=0.137）水平呈正相关,差异均有统计学意义（P〈0.001）.[结论]延边地区小学生BMI和重要脂肪细胞因子的分布特征呈现明显的民族差异;BMI与不同脂肪细胞因子均存在显著相关性,且与不同脂肪细胞因子的相关性程度有所不同.

英文摘要：

OBJECTIVE To analyze the correlation of BMI with important adipocytokines in Korean- Chinese and Han nationality pupils of Yanbian area. METHODS A total of 3 879 elementary school students （2 011 of Korean-Chinese nationality and 1 868 of Han nationality） were selected from July, 2011 to July, 2012 in Yanbian area. Height and weight were measured. Serum adiponectin （ADP）, leptin （LEP） and tumor necrosis factor-α （TNF-α） were measured after 12 hours fasting. RESULTS The levels of BMI and LEP in Korean-Chinese nationality pupils were significantly higher than those in Han nationality pupils （FBMI = 121.07, FEEP = 90. 35, P〈0. 001）, and the level of ADP in Han nationality pupils was obviously higher than that in Korean-Chinese nationality pupils in Yanbian area （FADP = 89. 64, P〈 0. 001）. The levels of LEP and TNF-α were with the level of BMI （FLEP progressively higher 1 003.39, FTNF-α = 14. 55, P〈0.001）, and the level of ADP was progressively lower with the levels of BMI （FADP = 66. 27, P〈0. 001）. Spearman correlation analysis showed that BMI was positively related with LEP and TNF-α（r = 0. 428, 0. 130, P〈0.01）, and that was negatively related with adiponectin （r = -0. 195, P〈0.01）. The partial correlation analysis after the adjustment of age, gender, nationality and biochemical indexes showed that BMI was negatively related with adiponectin （r = - 0. 149）, and that positively related with LEP （ r = 0. 572） and TNF-α （ r = 0. 137）. All the results had the statistical significance（P〈0. 001）. CONCLUSION The distribution of BMI and important adipocytokines had significant nationality difference in the pupils of Yanbian area. There was a significant relationship between BMI and important adipocytokines, and BMI had different correlation degree with the different adipocytokines.