肌动朊细胞骨架是真核细胞的房间细胞骨架的一个重要部件并且是速度集合并且空间地由一系列肌动朊绑定蛋白质(ABP ) 控制。在 ABP 之中,当他们在 vivo 从 profilin 界限肌动朊水池装 nucleateunbranched 肌动朊细丝,在家庭蛋白质的形式吸引了许多注意。在最近的年里,一个数字 offormin 家庭从不同有机体的成员被报导了,并且他们的特征更清楚地被知道,尽管一些问题仍然是被澄清。这里,我们在家庭蛋白质总结结构,功能和不同形式的成核机制,打算比较他们并且给一些形式 ins 的学习的新线索。
The actin cytoskeleton is an important component of eukaryotic cell cytoskeleton and is temporally and spatially controlled by a series of actin binding proteins (ABPs). Among ABPs, formin family proteins have attracted much attention as they can nucleate unbranched actin filament from the profilin bound actin pool in vivo. In recent years, a number of formin family members from different organisms have been reported, and their characteristics are known more clearly, although some questions are still to be clarified. Here, we summarize the structures, functions and nucleation mechanisms of different formin family proteins, intending to compare them and give some new clues to the study of formins.