为建立猪带绦虫实验动物模型,本实验通过口服激活、未激活囊尾蚴和尾静脉注射激活的囊尾蚴感染昆明小鼠、BALB/c小鼠、SD大鼠、豚鼠、金黄地鼠、沙鼠,对各种鼠体内的绦虫的感染、生长发育及寄生部位等生物学特性进行研究。在感染45d的金黄地鼠体内检出可见虫体,检出的虫体多数吸附在小肠。本实验建立了猪带绦虫的实验动物模型,使得解决猪带绦虫实验材料的来源问题成为可能,也为猪带绦虫的深入研究奠定了基础。
To establish the animal models for Taenia solium, the Kunming mice, BALB/c mice, SD rats, guinea pigs, golden hamsters and gerbils were infected with activated or not activated cysticerci via oral and tail vein injection of activated cysticerci, respectively. The tapeworm infection, growth and development, and parasite location were examed in artificially infected animals. In addition, the visible parasites only detected in the golden hamster at 45 days post infection and the majority parasites were detected in the small intestine. The primary established animal model for T.solitun would facilitate further study for T.solium in vivo.