中文摘要：

由于终止码抑制技术（nonsense suppression technique）的发展，现在人们已能够将非天然氨基酸定点地（site-specifically）嵌入任何的功能蛋白质中^[1-3]。这项技术所带来的一个重要意义是给化学生物学家提供一种潜在、系统、精确地研究蛋白质结构与功能关系的工具^[4]。结合具有特殊光学的非天然氨基酸的设计合成与嵌入，科学家们可以利用相关的光谱学手段来探究目标功能蛋白质的内部活性结构，因此，设计和合成具有特殊光谱性质的的非天然氨基酸是合成化学家所感兴趣的课题。

英文摘要：

α-N-（ S-1-phenylethyl） -β- （4′-methoxyl） benzoyl-L-alanine had been synthesized by combination of Friedal-Craft reaction and stereo-selective Michael reaction. The structure was confirmed by 1H NMR, 13 C NMR and X-Ray single crystal diffraction. The steady-state fluorescence property of the title compound was also investigated. It was found that the maximum emission wavelength was longer and the quantum yield was less in solvents with larger dielectric constant. The title compound displayed recognition ability to environmental state.