中文摘要：

这研究被进行调查差别上的 qi，有营养的 yin 和激活的血循环和他们的相容性表示了的能够填满的中国植物的效果，并且探索内在的机制基因是从我们以前建立了的微分表示侧面被选择的化学家心肌层。尖锐心肌的梗塞( AMI )模型被绑扎建立左前面的下降(男孩)冠的动脉，然后，模型老鼠随机被划分成模型组， Metoprolol 组，填满的 qi 养育 yin ( RN )组，激活的血发行量( AB )组，和填满的 qi ，有营养的 yin 和激活的血循环( RA )组。另外，正常的组和假冒的组被建立。药组的老鼠被 intragastric gavage 在正常的组的操作，和老鼠以后在第二天与相应的药管理，假冒的组被给象一样的时间盐的正常。然后是化学家心在操作以后在第 8 天被收获。心肌的 pathomorphological 变化在一台轻显微镜下面被观察。象 COX5a 和 ATP5e 那样的目标基因的 mRNA 变化用实时荧光被检测量的 PCR (Q-PCR ) ，和相关的酶的活动被比色的试金检测。主要结果如下：组织学的变化被观察由他染色，并且胀大的 cardiocyte，煽动性的房间渗入和细胞溶解被显示出在地区性是模型组的化学家心肌层，当 pathomorphological 在所有药变化时，组们没显示出明显的变化。与精力新陈代谢， COX5a 和 ATP5e 有关的二基因，作为在在药组的 mRNA 水平下面调整的目标基因被选择。关联词的活动功能的酶也因此在模型组与那相比在 RA 组减少了(P【0.05 ) 。结果显示涉及精力新陈代谢小径的基因的反常表示能是 AMI 的分子的机制之一。能够填满的中国植物的相容性 qi，有营养的 yin 和激活的血循环影响精力亲戚基因 COX5a 的表示， ATP5e，它可能是心肌的保藏的机制，并且比填满的单个植物更有效 qi 和有营养的 yin 或激活血循环。

英文摘要：

This study was conducted to investigate the effects of Chinese herbs capable of replenishing qi, nourishing yin and activating blood circulation and their compatibility on differentially expressed genes of ischemic myocardium which were selected from differential expression profile we had established before, and to explore the underlying mechanism. The acute myocardial infarction （AMi） model was established by ligating the left anterior descending （LAD） coronary artery, then the model rats were randomly divided into the model group, the Metoprolol group, the replenishing qi nourishing yin （RN） group, the activating blood circulation （AB） group, and the replenishing qi, nourishing yin and activating blood circulation （RA） group. In addition, the normal group and the sham group were set up. The rats of medication groups were administered by intragastric gavage with corresponding drugs on the second day after operations, and the rats of the normal group and the sham group were given normal saline as the same time.Then the ischemic hearts were harvested on the 8th day after operation. The myocardial pathomorphological changes were observed under a light microscope. The mRNA changes of target genes such as COX5a and ATP5e were detected using Real-time fluorescence quantitative PCR （Q-PCR）, and the activities of related enzymes were detected by colorimetric assay. The main resuits were as follows： the histological changes were observed by HE staining, and cardiocyte swelling, inflammatory cell infiltration and cytolysis were showed in regional ischemic myocardium of the model group, while the pathomorphological changes in all medication groups did not show obvious changes. Two genes related to energy metabolism, COX5a and ATP5e, were selected as the target genes which were down-regulated at the mRNA level in the medication groups. The activities of correlative functional enzymes also decreased in the RA group compared to that in the model group accordingly （P〈0.05）. The results indicated