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缬沙坦氨氯地平片对正常高值血压的疗效临床观察
  • ISSN号:1000-1824
  • 期刊名称:延边大学医学学报
  • 时间:2012
  • 页码:279-281
  • 分类:R541.6[医药卫生—心血管疾病;医药卫生—临床医学;医药卫生—内科学]
  • 作者机构:[1]延边大学附属医院心内科,吉林延吉133000
  • 相关基金:国家自然科学基金资助,项目号:81160034.
  • 相关项目:CD-NP对慢性心力衰竭的疗效及作用机制的研究
中文摘要:

[背景]观察缬沙坦氨氯地平片对伴有头晕、头痛的正常高值血压的疗效.[病例报告]选择伴有头晕、头痛症状的正常高值血压患者68例,随机分为对照组和治疗组.对照组给予非药物治疗,治疗组给予非药物治疗加缬沙坦氨氯地平片.对照组总有效率为29.4%,治疗组为85.3%,治疗组总有效率明显高于对照组(P〈0.01).2组治疗后与同组治疗前比较,对照组收缩压(SBP)和舒张压(DBP)有所降低,但差异无统计学意义(P〉0.05);而治疗组SBP和DBP明显降低(P〈0.01).2组治疗后相比较,治疗组SBP和DBP明显降低(P〈0.01).[讨论]缬沙坦氯氯地平片复方制剂治疗伴有头晕、头痛症状的正常高值血压患者有效.

英文摘要:

BACKGROUND To investigate the therapeutic effects of valsartan and amlodipine tablets on the patients with dizziness, headache and high normal blood pressure. CASE REPORTS Sixty eight of patients with dizziness, headache and high normal blood pressure were selected and divided into two groups of control and treatment. The control group received non-drug therapy, and the treatment group received non-drug therapy added the valsartan and amlodipine tablets. The total effective rate was obviously higher in the treatment group (85.3%) than in the control group (29.4%, P%0.01). As compared between before and after treatment, the systolic blood pressure (SBP) and diastolic blood pressure (DBP) were somewhat decreased in the control group with no statistically significant difference (P ~ 0.05), but significantly decreased in the treatment group (P %0.01), and the SBP and DBP after treatment were significantly decreased in the treatment group than in the control group (P % 0.01). DISCUSSION The compound treatment of valsartan and amlodipine tablets has effectiveness for treatment the patients with dizziness, headache and high normal blood pressure.

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期刊信息
  • 《延边大学医学学报》
  • 主管单位:吉林省教育厅
  • 主办单位:延边大学
  • 主编:方金女
  • 地址:吉林省延吉市局子街1327号
  • 邮编:133000
  • 邮箱:yxxb@ybu.edu.cn
  • 电话:0433-2660262
  • 国际标准刊号:ISSN:1000-1824
  • 国内统一刊号:ISSN:22-1260/R
  • 邮发代号:12-35
  • 获奖情况:
  • 全国高等学校自然科学学报评比中获得二等奖,吉林省一级期刊
  • 国内外数据库收录:
  • 美国化学文摘(网络版)
  • 被引量:3577