目的了解3种侵人性产前诊断技术的成功率、有效性、安全性及其手术并发症。方法总结2010年1月至2012年12月广西壮族自治区妇幼保健院优生遗传门诊所进行的经腹绒毛穿刺、羊水穿刺、脐静脉穿刺手术病例,对其进行回顾性分析。结果3种侵入性产前诊断技术均能安全、有效地预防出生缺陷,羊水穿刺一次成功率最高,但流产率无显著性差异。结论侵入性产前诊断技术能安全有效地预防出生缺陷,值得推广。
Objective we analyzed the success rate, effectiveness, safety and complications of these in- vasive diagnostic techniques. Method Summarized all invasive prenatal diagnostic surgical cases of Ab- dominal CVS, amniocentesis and umbilical vein puncture of Guangxi MCH genetic clinics from January 2010 to December 2012. Results Three kinds of invasive prenatal diagnostic techniques can safely and ef- fectively prevent birth defects, amniocentesis with the highest success rate, There is no significant differ enee in the miscarriage rate. Conclusions Invasive prenatal diagnosis can safely and effectively prevent birth defects, and could be widely applied.