目的:报告5例卵巢硬化性间质瘤合并Meigs征及CA125升高的病例,分析其临床特点,为临床诊治提供依据。方法:对5例病例的临床表现、影像学、病理学等特点加以分析,并复习相关文献。结果:硬化性间质瘤合并Meigs征及CA125升高是一种极少见病例,腹水量与CA125水平正相关,与肿瘤大小无关。结论:硬化性间质瘤刺激腹膜导致腹膜产生腹水及分泌CA125可能是其合并Meigs征及CA125升高可能机制。
Objective:To analyze the clinical features of Meigs'syndrome with elevated serum CA125 levels in five cases of ovarian sclerosing stromal tumor. Methods: The chnical features of these five cases were analyzed and relative references were reviewed. Results: Sclerosing stromal tumor with Meigs syndrome and elevated CA125 is a rare condition. The volume of ascites is positively related with CA125 level and unrelated withtumor size. Conclusion: Peritoneum secretes more ascites and CA125 under the stimulation of sclerosin$ stromal tumor,which is probably the reason of Meigs~syndrome and elevated serum CA125 level.