目的:研究红树植物白骨壤(Avicennia marina)叶子部位次生代谢产物的结构多样性。方法:采用多种色谱方法进行分离纯化,通过波谱方法,并对照文献鉴定化合物结构。结果:分离并鉴定了21个苯丙素和萘醌类化合物,包括3个新化合物,分别是erythro-guaiacylglycerol-β-ferulic acid ether(1),marinnone A(16)和marinnone B(17);18个已知物,分别是threo-guaiacylglycerol-β-ferulic acid ether(2),eleutheroside E2(3),(+)-lirioresinol A(4),dihydroxymethyl-bis(3,5-dimethoxy-4-hydroxyphenyl)tetrahydrofuran-9-O-β-glucopyranoside(5),(+)-lyonire-sinol3α-O-β-D-glucopyranoside(6),(-)-lyoniresinol3α-O-β-D-glucopyranoside(7),epi-pinoresinol(8),leucosecepto-side A(9),jionoside C(10),salsaside A(11),ilicifolioside A(12),acteoside(13),isoacteoside(14),ethyl ferulate(15),avicennone D(18),avicenone E(19),avicennol C(20),stenocarpoquinone B(21),其中化合物1和2互为差向异构体,16和17互为同分异构体。结论:化合物1,16,17为新化合物,13个已知化合物2~12,14,15为首次从该属植物中获得。
Objective:To investigate the chemical constituents from Avicennia marina. Methods: The isolation and purification of the CH2Cl2 and n-BuOH fractions of this plant were performed, and the chemical structures were elucidated by spectral analysis as well as comparison of their spectral data with literature values. Results: Three novel compounds were obtained and identified as erythro-guaiacylglycerol-β-ferulic acid ether (1), marinnone A (16) and marinnone B (17) , along with eighteen known compounds as threo-guaiacylglycerol-β-ferulic acid ether (2), eleutheroside E2 (3), ( + )-lirioresinol A ( 4 ), dihydroxymethyl-bis ( 3, 5-dimethoxy-4-hydroxyphenyl ) tetrahydrofuran-9-O-β-glucopyranoside (5), ( + ) -lyoniresinol 3α-O-β-D-glucopyranoside ( 6 ), ( - ) -lyoniresinol 3α-O-β-D-glucopyranoside (7), epi-pinoresinol (8), leucoseceptoside A (9), jionoside C (10), salsaside A (11), ilicifolioside A (12), acteoside ( 13), isoacteoside ( 14), ethyl ferulate ( 15 ), avicennone D (18), avicenone E (19), avicennol C (20), and stenocarpoquinone B (21). Conclusion: Three new compounds ( 1, 16 and 17) were obtained and thirteen known compounds, 2 -12, 14 and 15 were isolated from Avicennia genus for the first time.