中文摘要：

目的探讨LVIS单支架辅助栓塞颅内多发动脉瘤的安全性及有效性。方法回顾性分析西南医科大学附属医院神经外科2014年10月至2016年4月收治的19例颅内多发动脉瘤经LVIS单支架一站式辅助栓塞2个动脉瘤的临床资料及影像学资料。结果本组19例患者共38个多发动脉瘤行LVIS单支架辅助栓塞。平均11个月的临床随访发现，临床预后良好率为79％（15／19）[改良Rankin量表（mRS）评分为0～1分]，轻残率为21％（4／19）（mRS评分为2～3分），无重残及死亡发生。6个月后的数字减影血管造影（DSA）随访结果显示完全栓塞率为87％（33／38），近全栓塞率为13％（5／38）。共4个动脉瘤在随访中发生动脉瘤内进一步血栓化形成，其瘤内进一步血栓化形成率占非完全栓塞患者的57％（4／7）。术中发生并发症3例，分别为术中动脉瘤破裂1例、脑血管严重痉挛1例及术中支架内血栓形成1例。结论LVIS单支架辅助栓塞颅内多发动脉瘤具有良好的安全性和有效性，但仍然不可忽视其症状性支架内血栓事件的发生。

英文摘要：

Objective To explore the safety and efficacy of single low-profile visualized intraluminal support（LVIS）-assisted coiling of multiple intracranial aneurysms. Methods Retrospective analysis of clinical data and radiographic data of 19 patients, who underwent one-stage aneurysm embolization of two intracranial aneurysms with single LVIS stent in the period from October 2014 to April 2016 at Department of Neurosurgery, Affiliated Hospital of Southwest Medical University. Results Nineteen patients were performed with stent-assisted coiling of multiple aneurysms using single LVIS. The average 11-month follow- up showed that good outcome （mRS： 0 - 1 ） was reported in 79% （15/19） of the cases. Mild disability （ mRS： 2-3） was observed in 21% （4/19） of the cases. No severe disability or death occurred. Six-month follow-up showed that complete embolization rate was 87% （33/38）assessed using DSA and nearly complete embolization rate was 13% （5/38）. A total of 4 aneurysms showed further progressed thrombosis during follow-up, and the incidence of further thrombosis was 57% （4/7）in patients with incomplete embolization. Intraoperative complications occurred in 3 patients which included 1 case of intraoperative rupture, 1 case of transient brain swelling and 1 case of intraoperative stent thrombosis. Conclusions Single stent-assisted coiling of multiple intracranial aneurysms using LVIS seemed to demonstrate safety and efficacy. However, the chance of symptomatic stent thrombosis could not be ignored.