中文摘要：

目的在中国泰州的中等收入人群中探索童年期社会经济地位（socioeconomic status,SES）与肥胖的关联。方法本研究的数据来自泰州健康人群跟踪调查（Taizhou Longitudinal Study,TZL）第Ⅲ期基线调查中35-64岁中年人的基线数据。普通型肥胖定义为BMI≥28.0 kg/m2,中心型肥胖定义为男性腰围（waist circumference,WC）≥90 cm、女性WC≥80 cm。以20世纪中期中国家庭三大件（自行车、手表和缝纫机）数量来定义SES水平：0件、1或2件、3件分别代表SES低、中、高水平。比较不同SES组间的差异,并用Logistic回归分析童年期SES与肥胖的关联。结果男性中普通型肥胖的比例为13.5%,中心型肥胖的比例为30.9%;女性中普通型肥胖的比例为13.6%,中心型肥胖的比例为53.7%。男性SES水平与BMI和WC成正相关。相对于童年期家庭三大件数量为0件的人,拥有3件的人中年期普通型肥胖的风险（OR=1.79,95%CI：1.40-2.28）和中心型肥胖的风险均增加（OR=1.48,95%CI：1.12-1.80）,在调节了年龄、婚姻状况、教育程度、家庭收入、吸烟饮酒状况和体力活动等混杂因素后,关联仍然显著。女性SES水平与BMI和WC成负相关。相对于童年期家庭三大件数量为0件的人,拥有3件的人中年期普通型肥胖（OR=0.72,95%CI：0.58-0.90）和中心型肥胖的风险（OR=0.45,95%CI：0.38-0.54）都降低。在调节了混杂因素后,与中心型肥胖的关联依然显著。结论在发展中国家中等收入人群中,童年期SES与肥胖的关联存在性别差异,即高SES增加男性肥胖的风险,而降低女性肥胖的风险。在社会经济由发展中阶段向发达阶段转变的同时,童年期SES与肥胖的关联也从正相关向负相关转变,这种转变较早发生在女性身上。

英文摘要：

Objective To explore the association between childhood socioeconomic status（ SES） and obesity in the population with medium-income in Taizhou,China. Methods All baseline data were derived from middle-aged population（ 35- 64 years old） in Phase Ⅲ of Taizhou Longitudinal Study（ TZL）. General obesity and central obesity were measured by body mass index（ BMI） ≥ 28. 0 kg/m2 and waist circumference（ WC） ≥90 cm for male and WC≥80 cm for female,respectively. Three simple in a family（ a watch,a sewing machine and a bicycle） which were appropriate in China of the mid-20 th century were chosen as the indicators of childhood SES： 0,1 or 2 and 3 on behalf of low,medium and high level. Logistic regression models were used to estimate the odds ratio（ OR） of the associations.Results The prevalence of general obesity and central obesity were 13. 5% and 30. 9% in males and 13.6% and 53. 7% in females. In males,childhood SES was associated positively with BMI and WC. The crude OR for general obesity was 1. 79（ 95% CI： 1. 40- 2. 28）,while for central obesity it was 1. 48（ 95% CI：1. 12- 1. 80）,which were both significant after adjusting for covariates,such as age,marriage status,education level,family income,smoking,alcohol intake and physical activity. In females,childhood SES was associated negatively with BMI and WC. Compared with SES 0 level,the crude OR for general obesity in SES3 level was 0. 72（ 95% CI： 0. 58- 0. 90）,while for central obesity it was 0. 45（ 95% CI： 0. 38- 0. 54）,and the latter was also significant after adjusting for the above factors. Conclusions The effects of childhood SES on the risk of obesity in the population with medium-income in developing country differed by gender,which means that males with high childhood SES and females with low childhood SES have higher risk of obesity. Following the economic development,the shift from positive correlation towards negative correlation between childhood SES and obesity may occur earlier in females than i