中文摘要：

瞄准：为了评估可行性，造影剂并且连续地的 n 在 PTL 期间与 SonoVue (登记) 设想了。VX2 肿瘤的边界是到肝实质和肿瘤的亢奋的拟声。在 PTL 期间与肝正常实质和肿瘤实质相比在为在注射以后的 VX2 肿瘤的边界的价值有有效差量。结论：PTL 是为在兔子的肝的 VX2 的肿瘤 lymphangiogenesis 的察觉的一个新奇方法。联合 PTL 和提高对比的 ultrasonographic 成像能改进肝癌症的诊断。并且经皮的 transhepatic lymphosonography (PTL ) 的功效作为为在兔子并且到的肝的 VX2 的肿瘤 lymphangiogenesis 的察觉的一个新奇方法为肝癌症的诊断评估联合 PTL 和平淡的提高对比的 ultrasonographic 成像。方法：有 VX2 肿瘤的十只兔子在这研究被包括。SonoVue (0.1 mL/kg ) 为提高对比的 ultrasonographic 成像经由一根耳朵静脉被注入每只兔子，并且 0.5 mL SonoVue 为 PTL 在 VX2 肿瘤附近被注入正常肝实质。图象或电影片断被存储为进一步的分析。结果：Ultrasonographic 成像显示出 VX2 肿瘤变化在兔子的肝的 5-19 公里。VX2 肿瘤分别地是到在早、以后的阶段的肝实质的亢奋的拟声和低亚硫酸钠拟声。肝的淋巴容器在注射以后立即被设想

英文摘要：

AIM： To evaluate the feasibility and efficacy of percutaneous transhepatic lymphosonography （PTL） as a novel method for the detection of tumor lymphangiogenesis in hepatic VX2 of rabbits and to evaluate combined PTL and routine contrast-enhanced ultrasonographic imaging for the diagnosis of liver cancer. METHODS： Ten rabbits with VX2 tumor were included in this study. SonoVue （0.1 mL/kg） was injected into each rabbit via an ear vein for contrast-enhanced ultrasonographic imaging, and 0.5 mL SonoVue was injected into the normal liver parenchyma near the VX2 tumor for PTL. Images and/or movie clips were stored for further analysis. RESULTS： UItrasonographic imaging showed VX2 tumors ranging 5-19 mm in the liver of rabbits. The VX2 tumor was hyperechoic and hypoechoic to liver parenchyma at the early and later phase, respectively. The hepatic lymph vessels were visualized immediately after injection of contrast medium and continuously vi- sualized with SonoVue during PTL. The boundaries of VX2 tumors were hyperechoic to liver parenchyma and the tumors. There was a significant difference in the values for the boundaries of VX2 tumors after injection compared with the liver normal parenchyma and the tumor parenchyma during PTL.CONCLUSION： PTL is a novel method for the detection of tumor lymphangiogenesis in hepatic VX2 of rabbits. Combined PTL and contrast-enhanced ultrasonographic imaging can improve the diagnosis of liver cancer.