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中文摘要：
目的探讨儿童川崎病（K）的临床特征及并发冠状动脉损害的高危因素。方法回顾性分析36例KD患儿的临床资料,根据有无合并冠脉病变分成CAL阳性组与CAL阴性组,结合患儿的发热时间、年龄、C-反应蛋白（CRR）、血沉、血小板、血红蛋白等资料,比较2组患儿各项指标间的差异,明确其与发生冠状动脉损害间的关系。结果 36例KD患儿均有发热,其中口腔黏膜改变27例,眼结膜充血27例,皮疹22例,颈淋巴结肿大15例,手足硬肿及指趾端脱皮17例,肛周潮红伴脱皮5例。超声心动检查,无冠脉病变21例,有冠脉病变15例;2组患儿的发热天数、血沉、CRP、血小板及血红蛋白比较,差异均有统计学意义（P〈0.05）。结论患儿的年龄、CRP、血沉、血小板、血红蛋白及发热持续时间等,均可作为KD并发冠状动脉损害的预测因子。
英文摘要：
Objective To explore clinical characteristics and risk factors of complicated coronary artery lesions of childhood Kawasaki Disease. Methods 36 children with Kawasaki disease were divided into CAL ＋ and CAL groups according to the presence of coronary lesions,their clinical data were analyzed retrospectively. The age,C- reactive protein,blood sedimentation,platelet,hemoglobin and duration of fever were compared between the two groups,so as to finding out their relationship with coronary artery lesions.Results Among the 36 patients of KD,all cases had fever,27 had oral mucosal changes,27 had conjunction hyperemia,22 had rash,15 had cervical lymphadenopathy,17 had hard swollen in hands,feet and scaling in finger tips and tiptoes and 5 had anal flushing with scaling. Upon echocardiography,21 had no CALs while 15 had complicated CALs. There were statistic difference in the age,ESR,CRP,platelet,hemoglobin and duration of fever between the two groups. Conclusion The age,CRP,blood sedimentation,platelet,hemoglobin and the duration of the fever can be used as predictors of complicated coronary artery lesions in childhood with Kawasaki disease.
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