以7-羧基喹啉为原料,经硝化、酯化、喹啉环和硝基的还原、磺酰化和烷基化反应合成了7个新型的甲磺酰基喹啉衍生物,其结构经1HNMR和LC—MS表征。
Seven novel methylsulfona-quinoline derivatives were synthesized by nitrification, esterifi- cation, the reduction of quinoline and nitro, sulfonylation and alkylation. The structures were characterized by 1H NMR and LC-MS.