作为与肿瘤转移密切相关的分子,整合素在肿瘤转移的全过程中起着至关重要的作用。开展以整合索为作用靶点的抗肿瘤转移药物研究有助于最终攻克肿瘤这一顽疾。本文围绕整合素与肿瘤转移之间的关系综述近年研究进展,并对以整合素为靶点的抗肿瘤转移的新药研究进行探讨。
As closely related tumor metastasis adhesion molecule, integrin plays a vital role in the whole process of tumor metastasis. The study of anti-tumor metastasis by integrins targeting will be helpful to cure finally. This review discribes the the relationship between integrins and tumor metastasis, and drugs development in anti-tumor metastasis by integrins targeting.