中文摘要：

报道了一种新颖的带吩噻嗪基团8-羟基喹啉衍生物抗氧化剂,该化合物通过5-氯甲基-8-羟基喹啉与吩噻嗪在有机碱三乙胺存在下的反应而制备,并通过核磁共振谱、红外光谱和元素分析进行了表征,其羟基扫描活性通过可见-紫外吸收光谱进行了测定,抗氧化活性用2,2-二苯基-1-苦基肼（DPPH）模型系统进行了测定。与叔丁对氧酚相比,5-吩噻嗪甲基-8-羟基喹啉表现出了很高的抗氧化活性,当其质量浓度分别为0.2,0.5,0.8和1.0mg/mL时,相应的最大自由基清除率分别37.55%,76.16%,83.94%和84.04%。

英文摘要：

A novel antioxidant 8-hydroxyquinoline derivative with phenothiazine group was reported.5-Phenothiazinyl- methylene-8-hydmxyquinoline（PMHQ） was synthesized from reaction of 5-chloromethyl- 8-quinolinol hydrochloride with phenothiazine in the presence of organic base triethylamine and characterized by NMR and IR spectrocopies along with micmanalyses. The hydroxyl radical scavenging activities were tested by UV-Vis spectrophotometry. The anfioxidant activities were detected with 2,2-diphenyl-1-picrylhydrazyl （DPPH） model system. Compared with butylated hydroxytoluene （BHT）, PMHQ showed relatively high oxidation resistance. When the mass concentrations were 0.2, 0.5, 0.8 and 1.0 mg/mL, the highest free radical scavenging rates of PMHQ were 37.55%, 76.16%, 83.94% and 84.04%, respectively.