中文摘要：

目的探讨血清小而密低密度脂蛋白（sdLDL）水平对颈动脉中内膜厚度（CA-IMT）的影响。方法行颈部动脉血管超声检查患者217例分为正常组（A组,113例,CA-IMT〈0.9mm）和增厚组（B组,104例,0.9mm≤CA-IMT≤1.5mm）。检测并分析血清sdLDL水平与CA-IMT增厚程度的相关性。结果B组血清sdLDL水平高于A组[（1.0±0.3）mmol/L vs.（0.8±0.4）mmol/L]（P〈0.05）。sdLDL水平增高者发生CA-IMT增厚的可能性是其正常者发生增厚的3.80倍。sdLDL水平与CA-IMT的增厚程度呈正相关（r=0.757,P〈0.01）。结论血清sdLDL增高是CA-IMT增厚的危险因素,与CA-IMT厚度有较高的相关性。

英文摘要：

Objective To explore the effect of serum small dense low density lipoprotein（sdLDL）on carotid artery intima-media thickness（CA-IMT）.Methods A total of 217 patients underwent carotid artery color Doppler ultrasound examination was assigned into two groups of A（CA-IMT〈0.9mm,113cases）and B（0.9mm≤CA-IMT≤1.5mm,104cases）.Serum level of sdLDL was detected and the correlation of serum sdLDL and CA-IMT was analyzed.Results Serum level of sdLDL in group B was higher than that in group A[（1.0±0.3）mmol/L vs.（0.8±0.4）mmol/L]（P〈0.05）.The possibility to have CA-IMT in the patients with high serum sdLDL was 3.80 times as that in those with normal serum sdLDL.Serum level of sdLDL was positively correlated with CA-IMT（r=0.757,P〈0.01）.Conclusion High serum level of sdLDL is a risk factor for CA-IMT thickening,which is positively correlated with CA-IMT.