含有功能侧基生物降解聚合物的制备在近几年中受到广大研究者的极大关注^[1,2]。目前已经通过环状碳酸酯与丙交酯(LA)和ε-己内酯(CL)等共聚的方法合成了带有羧基^[3-5]和羟基^[6,7]等的脂肪族聚酯,并在靶向载体、药物控释及组织工程方面得到了应用^[2,8]。但有关含侧链氨基的聚合物研究的报道很少,
Functionalized aliphatic polyesters, especially those with pendent hydroxyl, carboxyl and amino groups, have attracted much research interest in recent years due to their perfect biocompatibility, biodegradability and reactivity. Copolymerization of lactide with functionalized cyclic carbonate monomers proved to be an efficient way to functionalize aliphatic polyesters. However, random co-polyesters with pendent amino groups were seldom reported. This article reported a facile way to prepare aliphatic polyesters with random pendant azido and amino groups via Click reaction.