目的探讨黄曲酶毒素高暴露地区健康人群黄曲酶毒素B1(aflatoxin B1,AFB1)暴露的影响因素,为预防AFB1暴露提供依据。方法以广西南宁市居民为对象,通过问卷调查了解相关资料,采用竞争酶联免疫法检测血浆黄曲酶毒素B1白蛋白加合物(AFB1albumin adducts,AAA)水平,采用Bekman LX20 Chemistry Analyzer配套英国Randox公司诊断试剂检测肝功能。结果经济收入低、吸烟、饮酒、食用散装大米、大米保存超过30d、经常在外就餐的人群,AAA水平显著增高(P〈0.05)。结论人们经济收入水平及生活方式与AFB1暴露有关,食用散装大米、经常在外就餐、饮酒是AFB1暴露的危险因素。
Objective To investigate the influencing factors of aflatoxin B1 (AFB1) exposure in healthy people who lived in aflatoxin high-exposure area and to provide a basis for preventing AFBI exposure. Methods To the residents lived in the city of Nanning in Guangxi Province, a questionnaire survey was used to acquaint relevant information. The AFBl-albumin adducts (AAA)levels were screened by enzyme-linked immunosorbent assay and the liver function detected using a Bekman LX20 Chemistry Analyzer and diagnostic agents from Randox, UK. Results AAA level was significantly higher (P 〈 0. 05 ) in the people with lowincome, having habits of smoking, drinking, eating bulk rice, and eating rice that had been saved for a time of more than 30 days, and keeping regularly dining out. Conclusions The level of income and the lifestyle are related with Aflatoxin B1 exposure. The risk factors about Aflatoxin B1 exposure include consumption of bulk rice, regularly dining out, and drinking.