中文摘要：

后发性白内障（posterior capsular opacification,PCO）是现代白内障术后最常见的主要并发症之一.Smad蛋白家族是转化生长因子-β（TGF-β）细胞内信号传导的重要因子.TGF-β/Smads信号传导通路在PCO中起着至关重要的作用,特别是各类Smads在TGF-β2的诱导中与PCO存在密切关系.本文就TGF-β/Smads与PCO的关系作一综述.

英文摘要：

The posterior capsule opacification（PCO）is one of the most mainly common complications after modern cataract surgery. Smad proteins family are important factors of intracellular TGF （transforming growth factor）-β signaling transduction. TGF-β/Smads signalling pathway is very important for PCO, especially all kinds of Smads are being close relationship with PCO in induction of TGF-β2.This article reviewed the relationship between TGF-β/Smads and PCO.