中文摘要：

qinghaosu (artemisinin ) 的一个范围类似物用黑暗汗衫氧从修改 dihydroqinghao 酸 / 醛被综合被触发离开 trioxane 形成的关键步。最新存取的 1,2,4-trioxanes 展示了在文学在很类似的类似物通过一张稳定的碳碳单身者契约从相应于 qinghaosu 的内酯羰基组的碳扩大而不是一张缩荃氧碳契约的方面链。分别地， Biotin 和各种各样的胺也通过这被连接到 qinghaosu 核心一线性在开发混血儿和潜在地有用的探针寻找的努力拴住在里面 vivo 目标。

英文摘要：

A range of qinghaosu （artemisinin） analogues were synthesized from modified dihydroqinghao acid/aldehyde using dark singlet oxygen to trigger off the key step of the trioxane formation. The newly accessed 1,2,4-trioxanes featured a side chain extended from the carbon corresponding to the lactone carbonyl group of qinghaosu through a stable carbon-carbon single bond instead of an acetal oxygen-carbon bond in most similar analogues in the literature Biotin and various amines were also connected to the qinghaosu core, respectively, through such a linear tether in efforts to develop hybrids and potentially useful probes in search of the in vivo targets.